Head of Translational Immunology & Systems Insights

Janux Therapeutics Inc.; San Diego (CA); On-site; USD 180,000 - 240,000; Full time

Benefits offered by this job

Annual bonus program

Incentive stock option plan

401k plan with flat non-elective...

Medical insurance (employer-paid)

Dental and vision insurance

HSA, FSA, and supplemental plans

Unlimited PTO

Holiday schedule; summer/winter break

Relocation assistance

Job summary

Janux Therapeutics, Inc. in San Diego, CA, seeks a senior leader to guide translational and systems immunology for ARM programs, translating emerging immunology into actionable strategies and integrated evidence.

The role will lead data analyses across scRNA-seq, CITE-seq, TCR-seq, and high-dimensional assays, mentoring scientists and collaborating with clinical and regulatory teams. You will drive integration of nonclinical, translational, and clinical evidence to inform program decisions in a

Qualifications

• Ph.D., MD, or equivalent in Immunology or related field.
• Extensive biotechnology/pharmaceutical translational immunology experience.
• Deep expertise in T-cell and B-cell biology.
• Ability to integrate complex high-dimensional datasets across non-clinical and clinical studies.
• Hands-on proficiency with single-cell sequencing and high-dimensional flow cytometry; ability to independently interrogate data is required.
• Experience leading multidisciplinary scientific teams and influencing in a matrixed drug-development environment.
• Excellent scientific judgment, communication, and presentation skills.

Responsibilities

• Lead immunology-focused nonclinical and clinical translational strategy for ARM programs, addressing key biological and clinical questions.
• Define immune-monitoring strategies to deepen understanding of mechanism, pharmacodynamics, activity, durability, resistance, and safety.
• Translate emerging science into focused hypotheses and analytical plans for Janux programs.
• Prioritize questions to differentiate ARM biology from other immunotherapy approaches and drive integrated evidence-generation strategies.

Skills

Immunology expertise

Data integration

Team leadership

Scientific communication

Bioinformatics supervision

Education

Ph.D./M.D. in Immunology or related

Tools

Single-cell sequencing

CITE-seq

TCR-seq

Flow cytometry

Proteomics

Job description

Janux Therapeutics, Inc. in San Diego, CA, seeks a senior leader to guide translational and systems immunology for ARM programs, translating emerging immunology into actionable strategies and integrated evidence.

The role will lead data analyses across scRNA-seq, CITE-seq, TCR-seq, and high-dimensional assays, mentoring scientists and collaborating with clinical and regulatory teams. You will drive integration of nonclinical, translational, and clinical evidence to inform program decisions in a