Head of Translational Biomarkers & Genomics

Otsuka Pharmaceutical Co., Ltd

Princeton (NJ)

On-site

USD 186,000 - 279,000

Full time

14 days+

A complete application in a minute

Tailored resume and cover letter, ready to send.

Get past ATS filters

Benefits offered by this job

Medical coverage

Dental coverage

Vision coverage

Prescription drug coverage

Life insurance

Disability insurance

Tuition reimbursement

Student loan assistance

401(k) match

Flexible time off

Paid holidays

Paid leave programs

Job summary

Otsuka Pharmaceuticals Co., Ltd. seeks a senior biomarker/genomics scientist to lead cross-functional teams in asset development with active biomarker projects and to drive integration of biomarkers into clinical trials.

You will help design translational plans, collaborate with external experts, and oversee multi-omics data analyses to support pharmacodynamics markers and patient enrichment strategies. The role emphasizes leadership, advanced genomics and biomarker expertise, and the ability to

Qualifications

PhD or MS in Life Sciences with at least 10 years of relevant experience in clinical science, clinical research or other relevant scientific field.
Managerial and supervisory experience.
Proven experience with designing and conducting biomarker and genomics research experiments and reviewing and interpreting data to support drug development and improve clinical trial design.
Strong experience with a broad range of biochemical, molecular and cellular assays and bioinformatics including RNA-Seq, Exome and Whole Genome Sequencing, high throughput proteomics, and multiplex flow cytometry.
Ability to manage and collaborate on multiple projects in different stages of development under strict deadlines and fluctuating priorities.
Experience in translating results published in the scientific literature to independently design, execute and interpret complex sets of experiments or procedures.
Excellent verbal and written communication skills, including communicating and presenting complex results and ideas.

Responsibilities

Leads and/or participates in internal cross functional project teams for asset development programs with active fluid biomarker projects
Manages team responsible for the selection and integration of biomarkers into clinical trials
Endorses mechanistic biomarker plans and subsequently manages the data generation for presentations and publications to increase brand growth
Initiates experimental design discussions based on existing gaps in clinical trial data and aids in development of biomarker and genomic research plans in collaboration with Bioanalysis, Genomics, and Biomarker Research department head, project teams, and external opinion leaders
Recommends to Sr leadership and defends clinical trial design elements, including indication selection, population selection, and biomarker assessments, as appropriate
Engage external investigators and collaborators to ensure translational biomarker plans are robust and impactful
Oversees the analysis of large datasets, such as multi-omics, to elucidate mechanism of action, identify fit‑for‑purpose pharmacodynamic markers, and enable patient stratification in clinical trials
Contributes expertise to support business development due diligence projects
Participates in feasibility for new technology tools
Outsources services and implements and/or develops tools required to support biomarker and genomics research
Recommends and defends emerging technology to support measurement in biological fluids in clinical trials