GMP Peptide Chemist: Synthesis, Purification & CMC

Discover International; Cape Coral (FL); On-site; USD 90,000 - 130,000; Full time

Job summary

Discover International in Southwest Florida is seeking a hands-on chemist to join our GMP peptide synthesis team. You'll synthesize peptides via SPPS, purify by HPLC, document batch records, and support validation activities as we build GMP capabilities for clinical programs.

The ideal candidate has 4–8 years of peptide synthesis experience in a GMP environment, strong documentation habits, and a chemistry degree (BS/MS/PhD). US work authorization is required; visa sponsorship is not available.

Qualifications

• 4–8 years’ hands-on peptide synthesis in a GMP environment.
• Practical experience with prep HPLC purification of peptides.
• Strong GMP documentation habits: batch records, deviations, root cause analysis, change controls.
• Exposure to process and cleaning validation, plus CMC writing.
• BS, MS or PhD in Chemistry or a related field.
• Must be authorized to work in the US. Visa sponsorship is not available.

Responsibilities

• Run GMP synthesis of peptides by solid-phase peptide synthesis (SPPS), including cleavage and work-up
• Purify peptides by preparative HPLC, then lyophilize and package them
• Execute, and help write, master and executed batch records
• Support process validation and cleaning validation activities
• Own deviations, root cause investigations, CAPAs and change controls
• Contribute to CMC documentation for regulatory filings
• Work closely with R&D peptide chemistry, analytical and QA teams

Skills

GMP documentation

Root cause analysis

Change controls

Synthesis expertise

Education

BS/MS/PhD in Chemistry

Tools

Prep HPLC

Job description

Discover International in Southwest Florida is seeking a hands-on chemist to join our GMP peptide synthesis team. You'll synthesize peptides via SPPS, purify by HPLC, document batch records, and support validation activities as we build GMP capabilities for clinical programs.

The ideal candidate has 4–8 years of peptide synthesis experience in a GMP environment, strong documentation habits, and a chemistry degree (BS/MS/PhD). US work authorization is required; visa sponsorship is not available.