Global MSAT Director — Cell Therapy Manufacturing

AstraZeneca; Gaithersburg (MD); On-site; USD 217,000 - 325,000; Full time

Job summary

AstraZeneca is seeking a Senior Director of Manufacturing Science and Technology (MSAT) to lead end-to-end cell therapy manufacturing globally. This senior technical leader will oversee tech transfer, process validation, commercialization, and lifecycle improvements across internal and external sites.

The role involves directing regulatory submissions (CMC), risk management, and cross-functional partnerships with Late-stage Process Development and Manufacturing Operations to ensure robust supply

Qualifications

• Leadership and mentoring of senior technical teams.
• Strategic MSAT planning across global sites.
• Hands-on experience with regulatory submissions (CMC).

Responsibilities

• Define and execute the Global MSAT function strategy for clinical and commercial stages.
• Build and develop a high-performing global MSAT team.
• Lead PPQ readiness and CPV strategies across sites.

Skills

Leadership

Strategic thinking

Cross-functional collaboration

Regulatory submissions

People development

Education

B.S./M.S./Ph.D. in engineering/biotech

Job description

AstraZeneca is seeking a Senior Director of Manufacturing Science and Technology (MSAT) to lead end-to-end cell therapy manufacturing globally. This senior technical leader will oversee tech transfer, process validation, commercialization, and lifecycle improvements across internal and external sites.

The role involves directing regulatory submissions (CMC), risk management, and cross-functional partnerships with Late-stage Process Development and Manufacturing Operations to ensure robust supply