Global Head of CNS

Piper Companies; North Carolina; Hybrid; USD 260,000 - 380,000; Full time

Benefits offered by this job

Remote work

Travel opportunities

Executive leadership role

Job summary

Piper Companies is seeking a Global Head of CNS to lead strategy, growth, and execution for CNS programs within a global CRO. The role partners with sponsors, leadership, and operations to shape portfolio strategy and drive client engagements.

The position is remote with travel for sponsor meetings and industry events. The successful candidate will bring 15+ years in clinical research, CNS expertise, and a strong track record in business development and cross-functional leadership.

Qualifications

• 15+ years of clinical research experience with CNS expertise.
• Experience across pharma, biotech, and CRO environments.
• Proven ability to influence executive stakeholders and drive decisions.
• Strong knowledge of clinical trials, drug development, and ICH-GCP.
• Excellent executive communication, presentation, and negotiation skills.
• Ability to travel for BD and sponsor engagements.

Responsibilities

• Lead global CNS strategy across clinical development and business growth.
• Serve as executive SME for CNS programs across neurology and related fields.
• Drive commercial growth through proposal strategy and bid defenses.
• Build executive-level relationships with sponsors and key opinion leaders.
• Provide oversight for multiple complex global programs.
• Collaborate with BD, Clinical Operations, Regulatory, and Leadership to deliver solutions.
• Represent the organization at industry conferences and client meetings.
• Support initiatives to strengthen market positioning and growth.

Skills

Therapeutic strategy

Business development

Sponsor relationships

ICH-GCP knowledge

Executive communication

Negotiation skills

Cross-functional leadership

Travel willingness

Education

Life sciences degree

Job description

Piper Companies is seeking a Global Head of CNS to provide strategic and commercial leadership for a growing global Clinical Research Organization (CRO). The Global Head of CNS will be responsible for driving the vision, growth, and execution of the organization's Central Nervous System (CNS) therapeutic area while partnering closely with executive leadership, sponsors, and operational teams. This individual will serve as the executive leader for CNS strategy, business development, portfolio growth, and client engagement across global clinical development programs.

Location: Remote

Work Arrangement: Fully Remote with occasional travel for sponsor meetings, bid defenses, industry conferences, and leadership meetings.

Responsibilities of the Global Head of CNS:

• Lead the global CNS therapeutic area strategy across clinical development, business growth, and operational excellence initiatives.
• Serve as the executive subject matter expert for CNS clinical development programs across neurology, psychiatry, neurodegenerative diseases, mental health disorders, and rare neurological indications.
• Drive commercial growth through proposal strategy, bid defenses, account expansion, and executive sponsorship of strategic pharmaceutical and biotechnology partnerships.
• Build and maintain executive-level relationships with sponsors, key opinion leaders, and industry stakeholders.
• Provide strategic oversight for multiple complex global clinical development programs and portfolios.
• Collaborate with Business Development, Clinical Operations, Biometrics, Medical Affairs, Regulatory Affairs, and Executive Leadership teams to deliver innovative clinical development solutions.
• Evaluate emerging scientific trends, competitive intelligence, and market opportunities within the CNS landscape.
• Develop and mentor therapeutic area leaders while building a high-performing global CNS organization.
• Represent the organization at industry conferences, scientific meetings, advisory boards, and client-facing events.
• Support strategic initiatives that strengthen market positioning and drive long-term organizational growth.

Requirements of the Global Head of CNS:

• Bachelor's or advanced degree in Life Sciences, Clinical Research, Medicine, Pharmacy, or a related field.
• 15+ years of clinical research experience with significant CNS therapeutic area expertise.
• Experience across pharmaceutical, biotechnology, and CRO environments strongly preferred.
• Demonstrated success leading therapeutic area strategy, business development initiatives, and global sponsor relationships.
• Extensive experience overseeing large, complex global clinical development programs and portfolios.
• Strong knowledge of clinical trials, drug development, and regulatory requirements including ICH-GCP.
• Proven ability to influence executive stakeholders and drive strategic clinical development decisions.
• Strong business development experience including proposal strategy, bid defenses, and account growth.
• Excellent executive communication, presentation, and negotiation skills.
• Proven success leading global, cross-functional teams and complex stakeholder environments.
• Ability to travel as needed for business development activities and sponsor engagement.

Compensation for the Global Head of CNS:

• Salary Range: $260,000 - $380,000 base salary
• Target Bonus: 25%
• Full Comprehensive Benefits: Health, Vision, Dental, PTO, Paid Holidays, and Retirement Benefits
• Executive Leadership Opportunity within a Growing Global CRO

Keywords:

Global Head of CNS, CNS Therapeutic Area Leadership, Clinical Development, CRO, Neurology, Psychiatry, Neuroscience, Neurodegenerative Diseases, CNS Clinical Trials, Clinical Research, Drug Development, Business Development, Therapeutic Area Strategy, Portfolio Leadership, Executive Leadership, Sponsor Relations, Pharmaceutical Research, Biotechnology, Clinical Operations, ICH-GCP, Global Clinical Development, Proposal Strategy, Bid Defense, Clinical Program Leadership, Neuroscience Research

This job opens for applications on 11/03/2026. Applications for this job will be accepted for at least 30 days from the posting date.

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