Clinical Project Manager, CNS - 177500

Piper Companies; United States; Remote; USD 150,000 - 200,000; Full time

Benefits offered by this job

Health insurance

Vision insurance

Dental insurance

PTO and holidays

Job summary

Piper Companies is seeking a Clinical Project Manager, CNS to lead CNS-focused clinical research programs for a leading pharmaceutical/biotech organization. The role manages trial operations, ensures milestones, and coordinates cross-functional teams to drive successful development initiatives.

The ideal candidate has 8+ years in clinical research or PM within pharma/CRO, deep CNS trial experience, strong knowledge of GCP/ICH and FDA regulations, and a track record of managing budgets,

Qualifications

• 8+ years of clinical research or clinical project management experience.
• Extensive CNS clinical trial experience (neurology/psychiatry).
• Strong knowledge of GCP, ICH guidelines, FDA regulations, and trial processes.
• Proven experience managing CROs, vendors, and cross-functional teams.
• Ability to manage complex programs, budgets, and timelines.
• Excellent communication, organizational, and stakeholder management skills.

Responsibilities

• Lead planning, execution, and oversight of Phase I-IV CNS trials across multiple sites.
• Manage study timelines, budgets, resources, and CRO relationships.
• Collaborate with clinical operations, regulatory affairs, data management, biostatistics, and medical affairs.
• Monitor progress, identify risks, and implement mitigation strategies.
• Ensure compliance with ICH-GCP guidelines and FDA regulations.
• Oversee CRO activities across study start-up, enrollment, monitoring, and closeout.
• Prepare and present project updates and metrics to stakeholders and leadership.
• Support inspection readiness and audit preparation.

Skills

GCP knowledge

ICH guidelines

FDA regulations

Stakeholder management

Communication

Education

Bachelor's degree in Life Sciences / Nursing / Pharmacy

Advanced degree preferred

Tools

CTMS

EDC platforms

Clinical trial management tools

Job description

Piper Companies is seeking a Clinical Project Manager, CNS to lead and oversee clinical research programs focused on central nervous system (CNS) therapeutic areas for a leading organization within the pharmaceutical and biotechnology industry. The Clinical Project Manager, CNS will be responsible for managing clinical trial operations, ensuring study milestones are achieved, and coordinating cross-functional teams to support successful clinical development initiatives.

Responsibilities of the Clinical Project Manager, CNS:

• Lead the planning, execution, and oversight of Phase I-IV CNS clinical trials across multiple sites.
• Manage study timelines, budgets, resources, and vendor relationships to ensure project success.
• Collaborate with clinical operations, regulatory affairs, data management, biostatistics, and medical affairs teams.
• Monitor study progress, identify risks, and implement mitigation strategies to maintain project timelines.
• Ensure compliance with ICH-GCP guidelines, FDA regulations, and applicable industry standards.
• Oversee CRO activities and provide leadership during study start-up, enrollment, monitoring, and closeout activities.
• Prepare and present project updates, metrics, and status reports to key stakeholders and executive leadership.
• Support inspection readiness and contribute to audit preparation activities.

Requirements of the Clinical Project Manager, CNS:

• 8+ years of clinical research or clinical project management experience within the pharmaceutical, biotechnology, or CRO industry.
• Extensive experience managing CNS clinical trials, including neurology, psychiatry, or related therapeutic areas.
• Strong knowledge of GCP, ICH guidelines, FDA regulations, and clinical trial processes.
• Proven experience managing CROs, vendors, and cross-functional clinical teams.
• Demonstrated ability to manage complex clinical programs, budgets, and timelines simultaneously.
• Excellent communication, organizational, and stakeholder management skills.
• Bachelor's degree in Life Sciences, Nursing, Pharmacy, or a related field; advanced degree preferred.
• Experience with CTMS, EDC platforms, and clinical trial management tools.

Compensation for the Clinical Project Manager, CNS:

• Salary range: $150,000 - $200,000 base salary
• Full Comprehensive Benefits: Health, Vision, Dental, PTO, Paid Holiday and Sick Leave if Required by Law.

Keywords:

• Clinical Project Manager, CNS, Central Nervous System, Clinical Trials, Clinical Operations, Pharmaceutical Industry, Biotechnology, CRO Management, Neurology, Psychiatry, Clinical Research, Project Management, ICH-GCP, FDA Regulations, Phase I, Phase II, Phase III, Phase IV, Vendor Management, CTMS, EDC, Risk Management, Study Start-Up, Clinical Development, Site Management, Regulatory Compliance, Cross-Functional Leadership, Clinical Program Management

This job opens for applications on 10/30/2026. Applications for this job will be accepted for at least 30 days from the posting date.

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