Global Head of CGT Operations Excellence & Transformation

Lonza

Houston (TX)

On-site

Confidential

Full time

14 days+
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Job summary

Lonza is seeking a Global Head of Operational Excellence & Transformation to lead the CGT transformation strategy across a global manufacturing network. The role emphasizes governance, continuous improvement, and building capability across sites to drive reliability and scalability.

Qualified candidates will have senior leadership experience in regulated manufacturing, strong Lean/Six Sigma expertise, and a track record of delivering measurable value through global programs and digital

Qualifications

  • Bachelor's degree in Science, Engineering, Technology, Business, Operations Management, or related field; MBA preferred.
  • Significant leadership experience within biopharmaceutical, biotechnology, cell and gene therapy, or other regulated manufacturing environments.
  • Proven success leading global Operational Excellence, productivity, and transformation programs across multi-site manufacturing networks.
  • Deep expertise in Lean, Six Sigma, continuous improvement, process optimization, and operational performance management.
  • Strong knowledge of digital transformation, automation technologies, manufacturing systems, and data-driven decision-making.
  • Experience developing and implementing global training, capability-building, and workforce development programs.
  • Demonstrated ability to lead complex, cross-functional initiatives that deliver measurable business value and sustainable results.
  • Strong understanding of GMP requirements, regulatory expectations, and quality systems within regulated manufacturing environments.

Responsibilities

  • Define and execute the global CGT transformation strategy, including governance, prioritization, and long-term roadmap development.
  • Lead Operational Excellence, Digitalization, Training, and Productivity Improvement initiatives across the global manufacturing network.
  • Drive continuous improvement, productivity, cost optimization, and operational performance through Lean, Six Sigma, and other best-practice methodologies.
  • Champion digital transformation by implementing advanced technologies, automation, and data-driven solutions that improve reliability, efficiency, and flexibility.
  • Establish and oversee global training and capability-building programs to ensure workforce readiness and standardized competency development.
  • Identify, prioritize, and deliver high-impact strategic initiatives using robust project management and LBMS methodologies to achieve sustainable business outcomes.
  • Drive manufacturing innovation and adoption of emerging technologies and industry best practices to enhance scalability and competitiveness.
  • Lead, develop, and support global and site-based Operational Excellence, Transformation, Training, and Project Management teams.
  • Establish governance frameworks that promote harmonization, standardization, and consistent execution across all CGT sites.
  • Build strong partnerships with Manufacturing, MSAT, Quality, Regulatory, Engineering, EHS, Supply Chain, and Group Operations to ensure alignment and compliance.
  • Monitor, measure, and communicate the performance and business impact of transformation initiatives through KPIs, reporting, and governance reviews.
  • Serve as a key change leader, fostering a culture of operational excellence, accountability, collaboration, and continuous improvement throughout the global network.

Skills

Leadership
Lean & Six Sigma
Global program management
Digital transformation
GMP knowledge
Strategic planning
Cross-functional collaboration
Change management

Education

MBA or equivalent
Bachelor's degree in Science/Engineering/Business

Tools

GMP systems
Automation technologies
Data analytics platforms

Job description

Lonza is seeking a Global Head of Operational Excellence & Transformation to lead the CGT transformation strategy across a global manufacturing network. The role emphasizes governance, continuous improvement, and building capability across sites to drive reliability and scalability.

Qualified candidates will have senior leadership experience in regulated manufacturing, strong Lean/Six Sigma expertise, and a track record of delivering measurable value through global programs and digital

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