Director, Global Supply Chain – Operational Excellence (LEAN)

Scorpion Therapeutics

United States

On-site

USD 140,000 - 195,000

Full time

14 days+
Application generator

Don’t send a generic resume — generate a resume and cover letter tailored to this exact role.

Get past ATS filters

Job summary

Scorpion Therapeutics is seeking a Senior Leader to own the Operational Excellence roadmap across Supply Chain, External Manufacturing, and Technical Operations. The role focuses on transforming reliability, agility, and cost through end-to-end process improvements and data-driven decisions.

You will embed a culture of continuous improvement, coach leaders on OpEx mindsets, and collaborate with CMOs/CDMOs to ensure regulatory compliance and performance excellence in a fast-paced, global

Qualifications

  • Bachelor's degree in Engineering, SCM, Life Sciences, or related field.
  • 8–10 years in regulated healthcare, pharma development, supply chain, or manufacturing with 5–10 years in operational excellence.
  • Certified Lean Six Sigma Black Belt (or equivalent) strongly preferred.
  • Strong understanding of cGMP, regulatory requirements, and external manufacturing complexities.
  • Proven record improving operational performance, reducing costs, and increasing process efficiency.

Responsibilities

  • Develop and execute the Operational Excellence roadmap for supply chain, external manufacturing, and technical operations.
  • Drive initiatives to improve reliability, agility, and cost across the end-to-end supply network.
  • Embed a culture of continuous improvement across internal teams and external partners.
  • Monitor industry trends and benchmark performance to sustain operational advantage.
  • Identify, prioritize, and implement process improvements to enhance service, reduce costs, and ensure compliance.

Skills

Lean Six Sigma
Stakeholder management
Project facilitation
cGMP knowledge
External manufacturing
Data-driven decision making

Education

Bachelor's degree in Engineering/Life Sciences/related field
MBA or Master's preferred

Job description

Responsibilities:
  • Develop and execute the Operational Excellence roadmap for Supply Chain, External Manufacturing, and Technical Operations aligned with business priorities.
  • Drive transformational initiatives to improve reliability, agility, and cost-effectiveness across the end-to-end supply network.
  • Embed a culture of continuous improvement across internal teams and external partners.
  • Monitor industry trends and benchmark performance to sustain operational advantage.
  • Identify, prioritize, and implement process improvements to enhance service, reduce costs, and ensure compliance across planning, sourcing, manufacturing, and distribution.
  • Facilitate cross-functional projects using Lean, Six Sigma, Value Stream Mapping, and other methodologies.
  • Support Technical Operations problem-solving by coaching teams to apply fit-for-purpose root cause frameworks.
  • Standardize and digitize key supply chain and manufacturing processes to improve visibility and decision-making.
  • Collaborate with CMOs/CDMOs to assess/improve external manufacturing performance via KPI reviews and improvement plans; lead joint improvements ensuring cGMP and regulatory compliance.
  • Design and sustain a Tiered Management System (Tier 1-3), with visual performance management, dashboards, training/coaching, and effective escalation/feedback loops.
  • Build capabilities through training; coach leaders on OpEx mindset; lead change management; model data-driven, collaborative continuous improvement.
Qualifications & Experience:
  • Bachelor's degree in Engineering, Supply Chain Management, Life Sciences, or related field (required); Master's degree or MBA preferred.
  • 8-10 years in a regulated healthcare segment (pharma development, supply chain, manufacturing, medical device, or technical operations), including 5-10 years in operational excellence/continuous improvement or similar leadership.
  • Strong understanding of manufacturing/supply chain processes, cGMP, regulatory requirements, and external manufacturing complexities.
  • Certified Lean Six Sigma Black Belt (or equivalent) strongly preferred.
  • Proven record improving operational performance, reducing costs, and increasing process efficiency.
  • Experience managing/improving external manufacturing or supplier relationships.
  • Exceptional project/change/facilitation skills; strong communication/influencing/stakeholder management; ability to thrive in fast-paced global matrix environments.
Get your free, confidential resume review.
or drag and drop your file here.
Similar jobs

Similar jobs worth comparing

Director, Global Supply Chain Excellence & Digital Enablement Lead
Director, Global Supply Chain Excellence & Digital Enablement Lead

Scorpion Therapeutics • Conshohocken

On-site
USD 150,000 - 190,000
Director of Business Excellence
Director of Business Excellence

Jobtailor • Town of Florida (NY)

On-site
USD 180,000 - 240,000
Executive Director, Global Lean Operations
Executive Director, Global Lean Operations

LDI Search LTD. • California (MO)

On-site
USD 110,000 - 150,000
Competitive compensation
Long-term incentives
Executive benefits
Site Operational Excellence Lead
Site Operational Excellence Lead

Solesis • Quakertown

On-site
USD 115,000 - 165,000
Associate Director, Operational Excellence - Productivity
Associate Director, Operational Excellence - Productivity

Scorpion Therapeutics • Madison (NJ)

On-site
USD 120,000 - 160,000
Health coverage
401(k) plan
Paid time off
Site Operational Excellence Lead
Site Operational Excellence Lead

Secant Group • Quakertown

On-site
USD 80,000 - 100,000
Director, Global Supply Operations
Director, Global Supply Operations

Jobtailor • Cambridge (MA)

On-site
USD 180,000 - 240,000
Director, Site Operations & Strategic Execution
Director, Site Operations & Strategic Execution

Scorpion Therapeutics • Salt Lake City (UT)

On-site
USD 180,000 - 240,000
Competitive total rewards package, 401
Site Operational Excellence Lead
Site Operational Excellence Lead

Secant Group, LLC • Quakertown

On-site
USD 85,000 - 105,000
Director, Global Supply Chain Excellence (LEAN)
Director, Global Supply Chain Excellence (LEAN)

Cytokinetics • South San Francisco (CA)

Hybrid
USD 223,000 - 261,000