Global Director, External Manufacturing & Supply Chain

Crispr Therapeutics Inc in; Boston (MA); Hybrid; USD 260,000 - 290,000; Full time

Benefits offered by this job

Equity

Bonus

Benefits package

Job summary

CRISPR Therapeutics, Inc. in Boston is seeking an Executive Director of External Manufacturing & Supply Chain to lead external manufacturing partnerships and clinical supply operations for allogeneic cell therapies and lipid nanoparticle programs.

The candidate will drive strategic partnerships with CMOs/CDMOs, oversee material management, shipping, labeling, and distribution, and.manage a multi-disciplinary team to deliver program objectives with a strong focus on cGMP compliance and risk

Qualifications

• 15–20+ years in biopharmaceutical manufacturing, technical operations, supply chain, or process development.
• Experience with third parties and CDMOs for manufacturing operations and clinical supply chain management.
• Ability to influence and communicate with senior management stakeholders.
• Willingness to travel domestically and internationally.
• Proven ability to mentor and develop a strong team.

Responsibilities

• Build and maintain strategic and operational relationships with CRISPR's CMOs.
• Manage CMO manufacturing operations and deliverables to ensure material supply and alignment with objectives.
• Oversee clinical supply activities across allogeneic and in vivo therapeutic areas.
• Direct drug product shipping, labeling, and distribution to worldwide clinical sites.
• Lead cross-functional teams and manage budgets with purchase requisitions and POs.
• Provide regulatory filing support (IND, BLA) as needed.
• Lead CMO due diligence during new supplier selection and assess risks.
• Coordinate governance meetings with CDMOs and vendors for program alignment.
• Champion a data-driven, collaborative, fast-paced learning culture.

Skills

Leadership

Strategic communication

Cross-functional collaboration

Mentoring

Problem solving

Education

BS/MS in Biology, Chemistry, Chemical/Biochemical Engineering or related scientific discipline

Advanced degree (PhD or MBA) preferred

Job description

CRISPR Therapeutics, Inc. in Boston is seeking an Executive Director of External Manufacturing & Supply Chain to lead external manufacturing partnerships and clinical supply operations for allogeneic cell therapies and lipid nanoparticle programs.

The candidate will drive strategic partnerships with CMOs/CDMOs, oversee material management, shipping, labeling, and distribution, and.manage a multi-disciplinary team to deliver program objectives with a strong focus on cGMP compliance and risk