Genomics Technologist - Full Time - Day Shift - Pittsburgh

Highmark Health; Pittsburgh (Allegheny County); On-site; USD 65,000 - 90,000; Full time

Job summary

Highmark Health in Pittsburgh is seeking a Molecular Diagnostics Laboratory Technologist to perform high-complexity testing of patient DNA/RNA using NGS, PCR and related platforms. You will handle specimen processing, library preparation, sequencing, data review, and instrumentation troubleshooting.

You will maintain documentation, participate in assay validation, quality improvement, and ensure compliance with CLIA, CAP and HIPAA standards.

Qualifications

• Bachelor’s degree in biology, chemical, physical or clinical laboratory science.
• 1 year of experience in a Molecular Diagnostic Laboratory.
• Master’s in Human Genetics, Genomics preferred.
• ASCP or equivalent certification.
• 1 year of experience in a clinical Molecular Diagnostics Laboratory.

Responsibilities

• Perform high complexity molecular testing including tissue preparation, DNA/RNA extraction, qPCR, NGS library prep, sequencing, and result analysis.
• Operate, maintain, calibrate, and troubleshoot molecular and genomics laboratory instrumentation.
• Analyze, review, and verify molecular and NGS data to ensure accuracy, quality, and regulatory compliance.
• Manage specimen processing, reagent preparation, inventory tracking, and detailed laboratory documentation.
• Participates in continuing education to ensure growth and development of the laboratory.

Skills

Molecular Techniques

Statistical Analysis

Education

Bachelor’s degree in biology, chemical, physical or clinical laboratory science

Master’s in Human Genetics, Genomics

Job description

GENERAL OVERVIEW

This job independently performs specialized testing and analysis of patient DNA, RNA, and other genetic materials to support the diagnosis, prognosis, and treatment of inherited and acquired diseases. This role involves performing complex molecular and genomic testing using advanced technologies such as next-generation sequencing (NGS), PCR, and other molecular diagnostic platforms while ensuring compliance with regulatory and quality standards. The technologist is responsible for specimen processing, extraction, library preparation, sequencing, quality control documentation, data review, and troubleshooting of laboratory instrumentation and assays. They work closely with laboratory staff, senior technologists, and pathologists, to ensure accurate and timely test results. Additionally, technologists maintain laboratory documentation, participate in assay validation and quality improvement initiatives, and adhere to CLIA, CAP, and other accreditation requirements.

ESSENTIAL RESPONSIBILITIES

• Perform high complexity molecular testing including tissue preparation, DNA/RNA extraction, qPCR, NGS library prep, sequencing, and result analysis.
• Operate, maintain, calibrate, and troubleshoot molecular and genomics laboratory instrumentation.
• Analyze, review, and verify molecular and NGS data to ensure accuracy, quality, and regulatory compliance.
• Manage specimen processing, reagent preparation, inventory tracking, and detailed laboratory documentation.
• Participates in continuing education to ensure growth and development of the laboratory.
• Other duties as assigned or requested.

QUALIFICATIONS

• Required Bachelor’s degree in biology, chemical, physical or clinical laboratory science.
• 1 year of experience in a Molecular Diagnostic Laboratory
• Preferred Master’s in Human Genetics, Genomics
• American Society for Clinical Pathology (ASCP) or equivalent Certification
• 1 year of experience in a clinical Molecular Diagnostics Laboratory

SKILLS

• Experience with Molecular Techniques
• Statistical Analysis

DISCLAIMER

The job description has been designed to indicate the general nature and essential duties and responsibilities of work performed by employees within this job title. It may not contain a comprehensive inventory of all duties, responsibilities, and qualifications required of employees to do this job.

COMPLIANCE REQUIREMENT

This job adheres to the ethical and legal standards and behavioral expectations as set forth in the code of business conduct and company policies. As a component of job responsibilities, employees may have access to covered information, cardholder data, or other confidential customer information that must be protected at all times. In connection with this, all employees must comply with both the Health Insurance Portability Accountability Act of 1996 (HIPAA) as described in the Notice of Privacy Practices and Privacy Policies and Procedures as well as all data security guidelines established within the Company’s Handbook of Privacy Policies and Practices and Information Security Policy. Furthermore, it is every employee’s responsibility to comply with the company’s Code of Business Conduct. This includes but is not limited to adherence to applicable federal and state laws, rules, and regulations as well as company policies and training requirements.

Highmark Health and its affiliates prohibit discrimination against qualified individuals based on their status as protected veterans or individuals with disabilities and prohibit discrimination against all individuals based on any category protected by applicable federal, state, or local law. We endeavor to make this site accessible to any and all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process, please contact the email below. For accommodation requests, please contact HR Services Online at [e-mail] California Consumer Privacy Act Employees, Contractors, and Applicants Notice Highmark Health is a national, blended health organization that includes one of America’s largest Blue Cross Blue Shield insurers and a growing regional hospital and physician network. Based in Pittsburgh, Pa., Highmark Health’s 35,000 employees serve millions of customers nationwide through the nonprofit organization’s affiliated businesses, which include Highmark Inc., Allegheny Health Network, HM Insurance Group, United Concordia Dental, HM Health Solutions and HM Home & Community Services.