Genomics Technologist - Full Time - Day Shift - Pittsburgh

Allegheny Health Network; Pittsburgh (Allegheny County); On-site; USD 90,000 - 120,000; Full time

Job summary

Allegheny Health Network is seeking a Molecular Diagnostics Technologist to perform high-complexity testing on DNA/RNA samples, including NGS and PCR workflows. You will work with clinicians and pathologists to ensure accurate results and maintain quality documentation.

The role requires a biology-related degree and experience in a molecular diagnostic lab; master’s degree is preferred. The position emphasizes regulatory compliance and continuous education within a CLIA/CAP framework.

Qualifications

• Bachelor’s degree in biology, chemical, physical or clinical laboratory science.
• 1 year of experience in a Molecular Diagnostic Laboratory

Responsibilities

• Perform high complexity molecular testing including tissue preparation, DNA/RNA extraction, qPCR, NGS library prep, sequencing, and result analysis.
• Operate, maintain, calibrate, and troubleshoot molecular and genomics laboratory instrumentation.
• Analyze, review, and verify molecular and NGS data to ensure accuracy, quality, and regulatory compliance.
• Manage specimen processing, reagent preparation, inventory tracking, and detailed laboratory documentation.
• Participates in continuing education to ensure growth and development of the laboratory.
• Other duties as assigned or requested.

Skills

Molecular testing

Lab documentation

Regulatory compliance

Education

Bachelor's degree in biology/related

Master's in Human Genetics/Genomics

Tools

NGS instruments

qPCR

PCR

Sequencers

Job description

GENERAL OVERVIEW
This job independently performs performs specialized testing and analysis of patient DNA, RNA, and other genetic materials to support the diagnosis, prognosis, and treatment of inherited and acquired diseases. This role involves performing complex molecular and genomic testing using advanced technologies such as next-generation sequencing (NGS), PCR, and other molecular diagnostic platforms while ensuring compliance with regulatory and quality standards.

Company
Allegheny Health Network
Job Description
GENERAL OVERVIEW
This job independently performs performs specialized testing and analysis of patient DNA, RNA, and other genetic materials to support the diagnosis, prognosis, and treatment of inherited and acquired diseases. This role involves performing complex molecular and genomic testing using advanced technologies such as next-generation sequencing (NGS), PCR, and other molecular diagnostic platforms while ensuring compliance with regulatory and quality standards.
The technologist is responsible for specimen processing, extraction, library preparation, sequencing, quality control documentation, data review, and troubleshooting of laboratory instrumentation and assays. They work closely with laboratory staff, senior technologists, and pathologists, to ensure accurate and timely test results. Additionally, technologists maintain laboratory documentation, participate in assay validation and quality improvement initiatives, and adhere to CLIA, CAP, and other accreditation requirements.
Essential Responsibilities

• Perform high complexity molecular testing including tissue preparation, DNA/RNA extraction, qPCR, NGS library prep, sequencing, and result analysis.
• Operate, maintain, calibrate, and troubleshoot molecular and genomics laboratory instrumentation.
• Analyze, review, and verify molecular and NGS data to ensure accuracy, quality, and regulatory compliance.
• Manage specimen processing, reagent preparation, inventory tracking, and detailed laboratory documentation.
• Participates in continuing education to ensure growth and development of the laboratory.
• Other duties as assigned or requested.
  

Qualifications
Required

• Bachelor’s degree in biology, chemical, physical or clinical laboratory science.
• 1 year of experience in a Molecular Diagnostic Laboratory
  

Preferred

• Master's in Human Genetics, Genomics