Genomics Data Analysis Lab Tech II

University of Southern California; Los Angeles (CA); On-site; USD 36,000 - 39,000; Full time

Job summary

University of Southern California seeks a Research Lab Technician II to support ongoing AML genomics and immunogenomics projects. You will perform molecular, cellular, and in vivo experiments and help run day-to-day lab operations in a translational genomics setting.

Your responsibilities include processing and QC of sequencing data, downstream analyses, and data management in a collaborative team environment.

Qualifications

• Associate's degree required or higher in a related field.
• Bachelor’s degree in biology or related field is commonly preferred.
• Experience with molecular biology techniques and data analysis is expected.

Responsibilities

• Process and QC next-generation sequencing data (RNA-seq, WES/WGS, ATAC-seq, ChIP-seq, single-cell) using established pipelines.
• Perform downstream analyses: differential expression, variant calling/annotation, pathway enrichment, clustering.
• Analyze data from high-throughput drug screens and preclinical studies; perform basic stats.
• Mine public omics resources (TCGA, BeatAML, GEO, DepMap) to support targets.
• Maintain and update analysis pipelines and scripts with version control.
• Organize datasets, sample metadata, and clinical annotations with IRB/data security compliance.
• Run jobs on USC HPC cluster and manage data storage.
• Prepare figures, tables, and summaries for meetings and manuscripts.

Skills

Laboratory techniques

Data organization

Communication skills

Independent and team work

Education

Associate's degree

Tools

STAR

DESeq2

GATK

Seurat

Bioconductor packages

SLURM

Job description

University of Southern California seeks a Research Lab Technician II to support ongoing AML genomics and immunogenomics projects. You will perform molecular, cellular, and in vivo experiments and help run day-to-day lab operations in a translational genomics setting.

Your responsibilities include processing and QC of sequencing data, downstream analyses, and data management in a collaborative team environment.