Entry-Level Downstream Purification Specialist

SIGNOBIO INC

Houston (TX)

On-site

USD 42,000 - 62,000

Full time

14 days+

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Benefits offered by this job

Free onsite parking
Free onsite gym
Career growth opportunities
World-class biotech campus

Job summary

Sino Biological Inc. in Houston, TX, is seeking an entry‑level Downstream Associate to support purification and quality control in a bioprocessing environment. You will perform chromatography‑based purification and QC testing under supervision, contributing to project timelines and product quality.

The role emphasizes meticulous documentation, collaboration across teams, and adherence to safety protocols. A bachelor’s degree in a related field and willingness to work flexible hours are required.

Qualifications

  • Bachelor’s degree in Biology, Biochemistry, Biotechnology, or a related field.
  • 0–3 years of relevant lab experience with basic protein purification knowledge.
  • Familiarity with chromatography systems such as FPLC or HPLC.
  • Experience with protein QC assays (SDS‑PAGE, HPLC‑SEC, endotoxin testing, ELISA) preferred.
  • Strong documentation and organizational skills; ability to work cross-functionally.

Responsibilities

  • Perform purification of recombinant proteins and antibodies using chromatography methods.
  • Execute downstream workflows to meet project specifications and client requirements.
  • Conduct protein QC tests (SDS‑PAGE, HPLC‑SEC, endotoxin assays, UV‑Vis) and analyze results.
  • Maintain accurate batch records and lab notebooks per internal standards.
  • Assist with calibration and maintenance of chromatography and analytical instruments.

Skills

Attention to detail
Documentation
Team collaboration
Communication

Education

Bachelor’s degree in Biology/Biochemistry/Biotechnology or related

Tools

FPLC/HPLC

Job description

Sino Biological Inc. in Houston, TX, is seeking an entry‑level Downstream Associate to support purification and quality control in a bioprocessing environment. You will perform chromatography‑based purification and QC testing under supervision, contributing to project timelines and product quality.

The role emphasizes meticulous documentation, collaboration across teams, and adherence to safety protocols. A bachelor’s degree in a related field and willingness to work flexible hours are required.

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