Entry-Level Upstream Bioprocess Associate

Sino Biological, Inc.; Houston (TX); On-site; USD 42,000 - 64,000; Full time

Job summary

Sino Biological, Inc. in Houston, TX, is seeking an entry-level Associate, Upstream. You will assist recombinant protein and antibody expression in mammalian cell cultures (HEK293/CHO) and support QC testing with emphasis on accuracy and documentation.

The role offers collaboration with project scientists, flexible weekend/shift options, and involvement in essential lab maintenance in a global biotech setting. Ideal for launch into an industrial biotechnology career.

Qualifications

• Bachelor’s degree in Biology, Cell Biology, Biochemistry, Biotechnology, or related field.
• 0-3 years of lab experience with mammalian cell culture; HEK293 and CHO preferred.
• Familiarity with suspension culture and aseptic techniques.
• Basic experience with analytical assays such as SDS-PAGE, HPLC-SEC, UV-Vis, or endotoxin testing is a plus.
• Strong attention to detail, documentation, and troubleshooting skills.
• Flexible and adaptable to varying schedules or project demands.
• Effective communication skills and the ability to work collaboratively in a team-oriented environment.
• Must be able to lift and move 25-50 lbs as needed.

Responsibilities

• Perform recombinant protein expression using mammalian systems such as HEK293 and CHO.
• Execute upstream workflows including cell thawing, expansion, transfection, and harvesting.
• Maintain lab cleanliness, including biosafety cabinets, incubators, and shared spaces.
• Handle and maintain cell cultures using proper aseptic techniques.
• Conduct protein quality control assays, including SDS-PAGE, HPLC-SEC, endotoxin testing, and UV-Vis measurements.
• Record data and observations in electronic lab notebooks accurately and promptly.
• Assist with media/reagent preparation, equipment setup, and maintenance tasks.
• Support instrument calibration, troubleshooting, and lab upkeep.
• Collaborate with downstream and cross-functional teams to ensure smooth project execution.
• Conduct product aliquoting to meet delivery timelines.
• Adhere to all safety and PPE protocols under federal, state, and local regulations.

Skills

Attention to detail

Documentation

Troubleshooting

Communication

Team collaboration

Flexibility

Education

Bachelor's degree in Biology/Cell Biology/Biochemistry/Biotechnology

Tools

SDS-PAGE

HPLC-SEC

UV-Vis

Endotoxin testing

Job description

Sino Biological, Inc. in Houston, TX, is seeking an entry-level Associate, Upstream. You will assist recombinant protein and antibody expression in mammalian cell cultures (HEK293/CHO) and support QC testing with emphasis on accuracy and documentation.

The role offers collaboration with project scientists, flexible weekend/shift options, and involvement in essential lab maintenance in a global biotech setting. Ideal for launch into an industrial biotechnology career.