Engineer I, Downstream Processing

DMC Biotechnologies, Inc.; Boulder (CO); On-site; USD 78,000 - 95,000; Full time

Benefits offered by this job

Full DMC Employee Benefits

Job summary

DMC Biotechnologies, Inc. seeks an Engineer I to join the Downstream Processing team in Boulder, CO. This hands-on, laboratory-based role supports the development and scale-up of purification processes for fermentation products.

You will work under guidance of experienced engineers and collaborate across the technical team to deliver robust purification strategies. The position is a 12-month project funded by a grant, with responsibilities spanning experiment planning, data analysis, and

Qualifications

• Bachelor's degree in chemical engineering or related discipline.
• Hands-on experience with unit operations such as membrane filtration, evaporation, distillation, crystallization, chromatography, reaction chemistry, and solid-liquid separation.
• Ability to safely operate laboratory equipment and execute written experimental procedures.
• Ability to analyze quantitative data, clearly document results, and draw data-driven conclusions.
• Strong organizational skills and ability to manage multiple experiments or priorities.

Responsibilities

• Support development and optimization of processes for purification of compounds from fermentation.
• Plan and execute laboratory experiments involving unit operations with guidance.
• Use analytical techniques to quantify compounds in complex mixtures.
• Analyze data, draw conclusions, and communicate results to the team.
• Maintain accurate experimental records, calculations, and summaries.
• Track important experimental parameters and data, focusing on mass balances and product quality.

Skills

Unit operations

Data analysis

Laboratory techniques

Cross-functional teamwork

Education

Bachelor's degree in chemical engineering

Tools

HPLC/UPLC

GC

Titrations

Spectrophotometry

Job description

$78,000-$95,000 annually, based on experience and position level

Full DMC Employee Benefits

Duration:

12-Month Project Position

Anticipated Start:

October 2026

About DMC Biotechnologies

DMC is a biotechnology company based in Boulder, CO, and RTP, NC. Our Dynamic Metabolic Control™ technology platform delivers robust and predictably scalable biocatalysts resulting in cost-competitive and sustainable processes for everyday chemicals. We are a multi-product bio-based chemical company, working ingeniously to reduce the cost of biochemicals for markets in animal feed, human nutrition, pharmaceutical materials, and chemical intermediates.

The Role

We are looking for an Engineer Ito join ourDownstream Processingteam inBoulder, Colorado.

This hands-on, laboratory-based role will support the development and scale-up of processes used to recover and purify products from fermentation. Engineer I will work under the guidance of experienced engineers and scientists while collaborating across the broader technical team.

Responsibilities will include planning and executing experiments, operating bench-scale processing equipment, analyzing data, documenting results, and contributing to the transfer of successful processes to pilot and commercial scale.

Please note that this position is supported by grant funding and is initially offered for a 12-month term, subject to the terms and duration of thegrant.

Responsibilities

• Support development and optimization of processes for the purification of compounds of interest from fermentation
• Plan and execute laboratory experiments involving unit operations with guidance, such as microfiltration/ultrafiltration, evaporation/distillation, preparative-scale chromatography, crystallization, and reaction chemistry
• Use analytical chemistry techniques such as HPLC/UPLC, GC, titrations, and spectrophotometry to quantify compounds of interest in complex mixtures
• Analyze experimental data, draw data-driven conclusions, and communicate results to the broader technical team
• Maintain clear and accurate experimental records, calculations, and technical summaries
• Effectively track important experimental parameters and data, with a focus on mass balances, product yield and product quality (purity)
• Support process modeling, including technoeconomic modeling of anticipated and/or established processes and performance metrics at commercial scale
• Prepare reagents and materials including media, buffers, and stock solutions
• Coordinate experimental schedules within a broader team
• Troubleshoot and improve experimental methods and downstream processes
• Maintain safe laboratory practices and contribute to a safe, clean, and organized work environment

Required Qualifications

• Bachelor's degree in chemical engineering or related discipline
• Hands-on experience with unit operations such as membrane filtration, evaporation, distillation, crystallization, chromatography, reaction chemistry, and solid-liquid separation
• Ability to safely operate laboratory equipment and execute written experimental procedures
• Ability to analyze quantitative data, clearly document results, and draw data-driven conclusions
• Strong organizational skills and ability to manage multiple experiments or priorities
• Effective written and verbal communication skills
• Ability to work collaboratively in a cross-functional team

Preferred Qualifications

• Relevant industry or internship experience
• Experience with HPLC, UPLC, GC, titrations, spectrophotometry, or other analytical methods
• Experience with process modeling, cost-of-goods analysis, and technoeconomic analysis
• Programming experience using Python or similar tools for automation, engineering calculations, and data analysis
• Experience developing Arduino or Raspberry Pi based systems
• Experience working with fermentation-derived products or complex biological mixtures

Our Commitment to Diversity, Equity, and Inclusion

We're actively taking steps to make sure our culture is inclusive and that our processes and practices promote equity for all, including people of color, people from working-class backgrounds, women, and members of the LGBTQ+ community. We welcome and encourage applications from people with these identities or members of other historically marginalized groups.

Research shows that women and people of color tend not to apply to jobs unless they believe they are 100% qualified and apply to fewer senior-level positions. With that in mind, we encourage you to apply if you're not sure whether you meet our qualifications. We'd love to have the opportunity to consider you.