Applications Engineer 3 - Bioprocessing

MilliporeSigma; Burlington (MA); On-site; USD 80,000 - 121,000; Full time

Benefits offered by this job

Health insurance

Paid time off

Retirement contributions

Job summary

MilliporeSigma is seeking a Bioprocessing Applications Engineer to lead hands-on studies focused on downstream processes and lentivirus workflows, with potential expansion to AAV, mAbs, mRNA, pDNA, and peptides. The role emphasizes understanding end-user needs and deploying process development expertise across prototype and commercial technologies.

Based in Burlington and Bedford, MA, the position involves cross-functional teamwork, experimental design, and communication of results through

Qualifications

• Bachelor’s degree with 5+ years of direct bioprocess development experience.
• Master’s degree with 4+ years of direct bioprocess development experience.
• PhD with 2+ years of downstream unit operations and analytical methods experience.

Responsibilities

• Work on a cross-functional team to deliver application studies using MilliporeSigma product portfolio.
• Plan, set up, and execute laboratory experiments to evaluate performance of new technologies or prototypes.
• Define process control strategies and design recipes for optimal operation of product offerings.
• Research literature and attend conferences to stay current with bioprocess end-user targets and needs.
• Deliver internal and external literature and presentations summarizing results with focus on technical performance.

Skills

Cross-functional teamwork

Problem solving

Data modeling

DoE

Statistical analysis

Communication

Education

Bachelor’s degree in Chemical/Biochemical Eng or related field

Master’s degree in Chemical/Biochemical Eng or related field

PhD in Chemical/Biochemical Eng or related field

Tools

HPLC

ELISA

Chromatography

Tangential Flow Filtration

Job description

Work Your Magic with us! Start your next chapter and join MilliporeSigma.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role

MilliporeSigma is looking for a Bioprocessing Applications Engineer to join the Downstream Focused Modalities Applications R&D organization. This individual will take the lead to drive the hands-on, process-focused scientific studies to evaluate prototype and commercialized products and technologies. Centered on understanding the end users’ pain points, goals, and needs, this role will leverage continuous development of process and unit operation expertise to design and execute applications studies which provide guidance for effective process development, optimization and deployment of MilliporeSigma technologies. This role has a focus on lentivirus manufacturing workflows, and potential to expand to other novel modalities such as AAV, novel mAbs, mRNA, pDNA, and/or peptides.

Responsibilities

• Work on a cross-functional team to deliver application studies using MilliporeSigma product portfolio
• Plan, set up, and execute laboratory experiments to evaluate the performance of new technologies, or new product or component prototypes for given application scenario
• Define process control strategies and design recipes and methods for optimal operation of MilliporeSigma product offerings
• Research literature and attend conferences to keep current with the bioprocessing end user’s process design targets, performance expectations, and general bioprocessing needs
• Deliver internal and external written literature and presentations evaluating product designs and/or summarizing experimental results with a focus on technical performance

This position will be based in both Burlington and Bedford, MA. This position may include domestic or international travel (5%).

Minimum Qualifications

• Bachelor’s degree in Chemical Engineering, Biochemical Engineering, Biochemistry or other Engineering or Science field with 5+ years of direct bioprocess development experience

OR

• Master’s degree in Chemical Engineering, Biochemical Engineering, Biochemistry or other Engineering or Science field with 4+ years of direct bioprocess development experience

OR

• PhD in Chemical Engineering, Biochemical Engineering, Biochemistry or other Engineering or Science field
• 2+ years of experience with setting up and executing downstream unit operations including Chromatography, normal flow filtration and Tangential Flow filtration
• 2+ years of experience in analytical methods and high throughput platforms with respect to downstream process development

Preferred Qualifications

• Hands on Pharmaceutical and/or Biotechnology industry experience
• Excellent problem solving & analytic skills, including data modeling, DoE, and/or statistical analysis
• Demonstrated ability to perform analytical assays using HPLC and ELISA methods
• Excellent teamwork, and facilitation skills
• Demonstrated ability to communicate effectively with peers, customers, vendors and supervisor
• Excellent ability to communicate through written reports, oral presentations, application notes, poster presentations, and similar media

Pay Range for this position: $80,300 - $120,500

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job‑related factors. Position may be eligible for sales or performance‑based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites.

What we offer

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!