Engineer 3 - Upstream Bioprocessing

Millipore Corporation; Bedford (MA); On-site; USD 86,000 - 150,000; Full time

Benefits offered by this job

Health insurance

PTO

Retirement contributions

Other perquisites

Job summary

MilliporeSigma in Bedford, MA is seeking an Engineer III for the Focused Modalities Applications group to deliver bioprocessing data and optimize novel modalities such as mAbs and cell therapies. You will plan, execute, and interpret lab, bench-, and pilot-scale bioreactor studies and mentor peers.

The role requires advanced degrees and strong cross-functional collaboration with downstream processing and PAT teams, along with GMP familiarity and a passion for process development.

Qualifications

• Bachelor's degree in Chemistry, Biochemistry, Process Engineering, Mechanical Engineering or other Life Science or Engineering Discipline with 7+ years of industry experience.
• Master’s Degree in Chemistry, Biochemistry, Process Engineering, Mechanical Engineering or other Life Science or Engineering Discipline with 4+ years of industry experience.
• PhD in Chemistry, Biochemistry, Process Engineering, Mechanical Engineering or other Life Science or Engineering Discipline with 2+ years of industry experience.

Responsibilities

• Plan, execute, and interpret lab, bench-, and pilot-scale bioreactor studies to evaluate new technologies.
• Mentor peers, synthesize end-user requirements, and expand capabilities in bioprocessing.
• Collaborate with downstream processing and PAT development teams to solve problems.

Skills

Upstream bioprocessing

Bioreactor operations

Design of experiments

Statistical analysis

Process development

Cell counting

GMP practices

Lab automation

Technology transfer

Team collaboration

Education

Bachelor’s Degree in Chemistry/Biochemistry/Process Engineering/Mechanical Engineering or related Life Science field

Master’s Degree in Chemistry/Biochemistry/Process Engineering/Mechanical Engineering or related Life Science field

PhD in Chemistry/Biochemistry/Process Engineering/Mechanical Engineering or related Life Science field

Job description

Work Your Magic with us! Start your next chapter and join MilliporeSigma. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role

We are seeking a dynamic and agile Engineer III to join the Focused Modalities Applications group within Process Solutions Product Development at MilliporeSigma in Bedford, MA. In this role, you will work within a matrixed team to deliver bioprocessing applications data that helps solve customer challenges and showcases the value of our commercial products for novel modality process optimization & manufacturing. Drawing on expertise in upstream bioreactor operations and bioprocess development, the successful candidate will plan, execute, and interpret laboratory, bench‑, and pilot‑scale bioreactor studies to evaluate new technologies and optimize processes for emerging modalities such as novel mAbs (bispecifics, multi‑specifics) and cell and gene therapies. This position supports team growth by mentoring peers, synthesizing end‑user requirements, and expanding capabilities to keep pace with state‑of‑the‑art developments and thought leadership in novel bioprocessing. The successful candidate will have a passion for process‑development, strong cross‑functional problem‑solving skills, and the ability to collaborate with experts in downstream processing and PAT development teams.

Who You Are

Minimum Qualifications:

• Bachelor’s Degree in Chemistry, Biochemistry, Process Engineering, Mechanical Engineering, or other Life Science or Engineering Discipline and 7+ years of industry experience.
• Master’s Degree in Chemistry, Biochemistry, Process Engineering, Mechanical Engineering, or other Life Science or Engineering Discipline and 4+ years of industry experience.
• PhD in Chemistry, Biochemistry, Process Engineering, Mechanical Engineering, or other Life Science or Engineering Discipline and 2+ years of industry experience.

Preferred Qualifications:

• Experience with planning and executing upstream unit operations including setup and operation of single use bioreactors across multiple scales.
• Strong expertise and hands‑on experience in upstream bioprocessing for CHO based systems including novel mAb applications (bispecifics/multi‑specifics); knowledge in cell and gene therapy applications a bonus.
• Proficient in optimizing and transferring mammalian bioprocesses from laboratory to large‑scale production platforms using scale‑up/scale‑down approaches and technology transfer.
• Exposure to some of the following analytical techniques: Cell counting, metabolite analysis, protein quantification, glycan and charge variant analysis; flow cytometry, PCR, and ELISA experience.
• Skilled in statistical analysis, experimental design, and design of experiments (DoE) approaches.
• Experience leading small to medium size projects; demonstrated ability to deliver on timelines while balancing scientific rigor and customer urgency.
• Effectively communicates through written reports, oral presentations, application notes, poster presentations, and similar media.
• Familiarity with lab automation and GMP practices.

Pay Range for this position: $85,500 - $149,800 / year

Benefits offered by the Company

• health insurance
• paid time off (PTO)
• retirement contributions
• other perquisites

What we offer

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!