Downstream Process Scientist II: Innovative Biotech CMC

AbbVie Inc.; Worcester (MA); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

Comprehensive benefits package

401(k) retirement plan

Paid time off

Job summary

AbbVie Inc. in Massachusetts is seeking a scientist to develop downstream processing and support CMC activities for pipeline programs. You will drive purification process development and contribute to tech transfer and process characterization.

The role emphasizes independent laboratory work, data analysis, and collaboration with cross-functional teams. Strong communication, problem-solving, and a results-driven mindset are essential.

Qualifications

• BS or MS in Biological sciences with focus in Immunology, Biochemistry, Molecular Biology, Cell Biology, or related discipline; typically 7+ years (BS) or 5+ years (MS) of lab experience.
• Solid understanding of downstream purification and process development.
• Excellent written and oral communication; capable of presenting to cross-functional teams.
• Experience with process intensification or modeling is preferred.
• Compliance with GxP, safety, and regulatory standards.

Responsibilities

• Develop robust downstream processes for early and late-stage programs.
• Drive purification process development within project timelines and improve tech transfer workflows.
• Optimize downstream unit operations using experimentation and modeling.
• Design and execute process development and characterization activities.
• Collaborate with cross-functional teams and publish/present findings as needed.
• Explore innovative technologies including AI, automation, and digital tools.
• Demonstrate initiative and problem-solving to overcome complex challenges.
• Maintain safety, quality, and regulatory compliance in all work.

Skills

Downstream process development

Independent laboratory work

Communication skills

Problem-solving

Team collaboration

Data analysis

Adaptability to new technologies

Education

B.S. in Biological Sciences

M.S. in Biological Sciences

Chemical engineering/biochemical engineering background preferred

Tools

Modeling approaches

Automation interest

Job description

AbbVie Inc. in Massachusetts is seeking a scientist to develop downstream processing and support CMC activities for pipeline programs. You will drive purification process development and contribute to tech transfer and process characterization.

The role emphasizes independent laboratory work, data analysis, and collaboration with cross-functional teams. Strong communication, problem-solving, and a results-driven mindset are essential.