Downstream Process Scientist I, AAV Purification

Forge Biologics; Grove City (OH); On-site; USD 55,000 - 75,000; Full time

Benefits offered by this job

Health insurance

Paid time off

Parental leave

Annual bonus opportunities

401(k) with company match

Onsite fitness facility

Employee Assistance Program

Job summary

Forge Biologics is seeking an Associate Scientist I to support downstream process development and purification activities in our Columbus, Ohio facility. You will work with cross-functional teams to learn, document, and optimize AAV purification processes under supervision.

The role emphasizes basic purification techniques, data analysis, and collaboration to advance gene therapy platform projects while adhering to safety and GMP readiness standards.

Qualifications

• Associate's, Bachelor’s or certification in Chemical Engineering, Biology, Molecular Biology, Virology, Biochemistry or related discipline or relevant coursework; 0–1 year of experience OR equivalent practical experience.
• Prior experience through internships, job shadowing, or on-the-job learning.

Responsibilities

• Learn and contribute to downstream process development activities with supervision.
• Build foundational skills in purification techniques such as buffer preparation, filtration, column chromatography, buffer exchange, clarification techniques, lab cleaning and routine equipment sanitization and monitoring.
• Abide by all safety protocols and contribute to lab maintenance activities.
• Collaborates with peers to support experiments and begins contributing to data discussions and problem-solving in team settings.
• Writes simple study plans, PowerPoint presentations and internal reports with guidance.
• Documents all work clearly and contemporaneously in lab notebooks and electronic systems, ensuring same-day data entry, accuracy and traceability.
• Develops understanding of downstream process development principles and learning how purification processes align with cGMP requirements.

Skills

Basic lab skills

Data analysis

PowerPoint

Downstream purification

Education

Bachelor’s or certification in Chemical Eng., Biology, Molecular Biology, Virology, Biochemistry

Tools

FPLC chromatography systems

Tangential flow filtration (TFF)

Job description

Forge Biologics is seeking an Associate Scientist I to support downstream process development and purification activities in our Columbus, Ohio facility. You will work with cross-functional teams to learn, document, and optimize AAV purification processes under supervision.

The role emphasizes basic purification techniques, data analysis, and collaboration to advance gene therapy platform projects while adhering to safety and GMP readiness standards.