Director of Quality & NPD Strategy & Portfolio

Madrigal Pharmaceuticals; Conshohocken (Montgomery County); On-site; USD 212,000 - 240,000; Full time

Benefits offered by this job

Equity

Bonus

Job summary

Madrigal Pharmaceuticals is seeking a senior QA leader to oversee development quality strategy and governance across the portfolio. This role partners with CMC and clinical teams to embed risk management early and enable smooth progression toward commercialization while ensuring audit-ready documentation.

The candidate will lead phase-appropriate QMS implementation, vendor oversight, and continuous improvement initiatives to increase predictability and right-first-time outcomes across multiple

Qualifications

• BS+ Life Sciences or Engineering (or related) degree.
• 12–15 years QA experience with significant portfolio leadership.
• Demonstrated people leadership and executive stakeholder influence.

Responsibilities

• Define development quality operating model, governance forums, and performance metrics.
• Prioritize portfolio support and mitigate risks with options.
• Produce deliverables such as portfolio dashboards, governance calendars, and risk briefs.
• Ensure vendor oversight, audits, issue management, and readiness deliverables.
• Maintain readiness for development inspections and submission support.
• Sponsor continuous improvement to improve cycle time and documentation.

Skills

People leadership

Executive stakeholder influence

QA portfolio management

Education

BS+ Life Sciences / Engineering (or related)

Tools

Veeva Vault Quality (eQMS)

Job description

Madrigal Pharmaceuticals is seeking a senior QA leader to oversee development quality strategy and governance across the portfolio. This role partners with CMC and clinical teams to embed risk management early and enable smooth progression toward commercialization while ensuring audit-ready documentation.

The candidate will lead phase-appropriate QMS implementation, vendor oversight, and continuous improvement initiatives to increase predictability and right-first-time outcomes across multiple