Director of Operational Excellence & Training

Tango Therapeutics Inc.; Boston (MA); On-site; USD 164,000 - 246,000; Full time

Job summary

Tango Therapeutics Inc. is seeking an Operations Excellence Lead to design, implement, and optimize standardized processes across Development, ensuring inspection readiness and scalable execution.

You will translate strategic goals into efficient workflows and lead training and change management initiatives. You will develop role-based curricula, define performance metrics, and collaborate across functions to drive continuous improvement and accountability in a regulated life sciences

Qualifications

• Bachelor’s degree required (Life Sciences, or related field).
• Advanced degree preferred (e.g., MBA, MSc).
• Certification or formal training in Operatin Excellence, Lean, Six Sigma, or Process Improvement preferred.

Responsibilities

• Own end-to-end design, implementation, and optimization of assigned process and system across Development.
• Translate strategic objectives into fit-for-purpose, standardized processes that are efficient, scalable, and inspection-ready.
• Define process standards, guidance, and performance measures, ensuring clarity of roles and accountability.
• Develop and deliver training on new/changed processes incl. compliance expectations, and inspection readiness behavior.
• Design and maintain role-based and process-based curricula, including onboarding.
• Identify inefficiencies, risks, and variability through data analysis and stakeholder input, and lead targeted improvement initiatives.
• Support functions in adopting new or improved processes through change management, training inputs, and practical guidance.
• Ensure processes are well documented, consistently applied, and auditable, supporting inspection readiness.
• Track and report process performance, improvement outcomes, and residual risks to Operatin Excellence & Clinical Compliance leadership.
• Act as a subject-matter expert and trusted advisor to functional teams on process excellence and operational rigor.
• Support Leadership in defining and executing the learning and capability-building strategy for Development functions.
• Support leadership in building a learning culture that reinforces accountability, consistency, and continuous improvement.

Skills

End-to-end design

Lean

Training design

Process documentation

KPIs & dashboards

Audit readiness

Change management

Stakeholder engagement

Influence without authority

Learning culture

Collaboration

Education

Bachelor’s degree in Life Sciences

Advanced degree preferred

Job description

Tango Therapeutics Inc. is seeking an Operations Excellence Lead to design, implement, and optimize standardized processes across Development, ensuring inspection readiness and scalable execution.

You will translate strategic goals into efficient workflows and lead training and change management initiatives. You will develop role-based curricula, define performance metrics, and collaborate across functions to drive continuous improvement and accountability in a regulated life sciences