Director of AI‑Driven App-SRE & Reliability

Caris Life Sciences; Irving (TX); Hybrid; USD 180,000 - 240,000; Full time

Job summary

Caris Life Sciences seeks an experienced Director of Application Reliability and Production Operations to lead the on-site/hybrid team responsible for the clinical software portfolio. You will define SLOs, manage on-call incidents, and drive automation with strong governance under FDA and SOX controls.

You will hire and develop the App-SRE team, coordinate deployments, and ensure audit-ready evidence across change processes. This role emphasizes AI-assisted practice and observability maturity.

Qualifications

• Bachelor's degree or equivalent practical experience in a technical field.
• 10+ years in SRE/DevOps/production operations.
• 4+ years in people-management within SRE/production-operations.
• Hands-on incident response experience at Tier 1 or critical systems.
• Experience defining SLOs, error budgets, and alerting in production.
• Experience building/ maturing production-support and on-call functions.
• Regulatory framework experience (FDA, SOX, CAP/CLIA, HIPAA) with audit-ready documentation.
• Experience applying AI-assisted practices to operations or engineering.

Responsibilities

• Own the production-support model for the clinical application portfolio, including on-call rotation and incident response playbooks.
• Define, audit, and enforce SLOs, error budgets, and availability targets with leadership; monitor health metrics.
• Lead incident response as commander or senior responder; coordinate cross-functional teams and drive remediation.
• Develop runbooks and automation; ensure safe execution within documented procedures.
• Drive automation-first operations; reduce toil and favor self-service tooling.
• Coordinate deployments with engineering; validate health and execute rollback decisions.
• Grow and mentor the App-SRE team; set performance expectations and career paths.
• Represent App-SRE in leadership forums and compliance audits; communicate risk clearly.
• Lead AI-first practices for runbook automation and incident analysis.

Skills

SRE leadership

Incident response

SLOs & error budgets

On-call management

Regulatory compliance

AI in operations

Education

Bachelor's degree in CS/Engineering

Tools

CI/CD tooling

Observability platforms

Automation tooling

Job description

Caris Life Sciences seeks an experienced Director of Application Reliability and Production Operations to lead the on-site/hybrid team responsible for the clinical software portfolio. You will define SLOs, manage on-call incidents, and drive automation with strong governance under FDA and SOX controls.

You will hire and develop the App-SRE team, coordinate deployments, and ensure audit-ready evidence across change processes. This role emphasizes AI-assisted practice and observability maturity.