Director, Immunology & Translational Research

BioSpace; San Diego (CA); On-site; USD 170,000 - 225,000; Full time

Benefits offered by this job

Bonus

Equity

Benefits

Job summary

Mirador Therapeutics, Inc., a clinical-stage precision medicine company based in San Diego, seeks a Director, Immunology with strong immunology and cell biology background to support target validation, early-phase antibody discovery, IND-enabling studies, and biomarker discovery.

The role requires leadership, strategic thinking, and the ability to work with ambiguity. You will design assays, guide translational strategies, manage CROs, mentor the team, and present findings to senior leadership.

Qualifications

• PhD or equivalent post-graduate degree in Immunology or related field with 12+ years of experience.
• Experience in discovery and translational immunology within autoimmunity and inflammation space.
• Prior people management experience and CRO/vendor management.

Responsibilities

• Lead immunology and cell biology strategy for target validation, mechanism-of-action characterization, and biomarker discovery across the portfolio.
• Design, develop, and oversee cell-based assays, including primary human immune cell and ex vivo models, for target validation and antibody candidate characterization.
• Direct immunological support for early-phase antibody drug discovery, including target engagement and functional potency assays.
• Drive the immunology and pharmacology components of IND-enabling studies, including biomarker strategy and translational assay development.
• Build, lead, and mentor a high-performing immunology team, including hiring and performance management.
• Manage CROs and external collaborators supporting immunology assay development and biomarker studies.
• Partner cross-functionally to align immunology strategy with program timelines and milestones.
• Apply immunology and inflammation expertise to inform lead optimization and clinical candidate selection.
• Present data and strategic recommendations to senior leadership to support portfolio decisions.
• Track emerging immunology science and technologies to inform program strategy.

Skills

Immunology

Cell biology

Leadership

Team management

CRO management

Cross-functional collaboration

Data interpretation

Communication

Drug development

IND enabling

Education

PhD in Immunology

Job description

Mirador Therapeutics, Inc., a clinical-stage precision medicine company based in San Diego, seeks a Director, Immunology with strong immunology and cell biology background to support target validation, early-phase antibody discovery, IND-enabling studies, and biomarker discovery.

The role requires leadership, strategic thinking, and the ability to work with ambiguity. You will design assays, guide translational strategies, manage CROs, mentor the team, and present findings to senior leadership.