Director, Discovery Biology & RNA Therapeutics

Executive Recruit

Boston (MA)

On-site

USD 250,000 - 360,000

Full time

2 days ago

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Job summary

Executive Recruit in Boston seeks a Director, R&D - Discovery Biology to lead the Discovery Biology group and advance programs from target validation through IND-enabling studies. This hands-on leadership role focuses on building a strong team, shaping discovery strategy, and collaborating with chemistry, translational medicine, CMC, and external partners.

The ideal candidate has a PhD and 10+ years in biotech/pharma, with 5+ years of people leadership and a track record of IND progression.

Qualifications

PhD in molecular biology, immunology, pharmacology, or related field.
10+ years of R&D experience with 5+ years in leadership.
Proven ability to advance discovery programs toward IND.
Experience with external CROs and budget management.
Strong communication in a matrixed, fast-paced environment.

Responsibilities

Lead and develop a team of scientists responsible for target validation, assay development, functional genomics, and mechanism-of-action studies.
Own discovery biology strategy for 2–3 pipeline programs and partner with project teams to set milestones and decision points.
Drive programs from lead optimization through IND-enabling studies, including pharmacology, biomarker strategy, and translational package design.
Manage external CROs and academic collaborators, including study design, timelines, budgets, and data quality.
Represent Discovery Biology on cross-functional program teams and contribute to regulatory documents and IND submissions.