Director, Commercial Supply Chain

UniQure NV; Lexington (MA); On-site; USD 205,000 - 265,000; Full time

Job summary

uniQure seeks a Director of Commercial Supply Chain to build, scale and manage global operations for high‑value gene therapies ahead of Phase 3 and commercialization. You will design the operating model, lead demand and supply planning, distribution, and cold‑chain logistics.

You will ensure GDP and DSCSA compliance, drive launch readiness, and lead cross‑functional teams across TechOps, Quality, Regulatory, and Finance, plus external partners, to mitigate risk and optimize inventory.

Qualifications

• Bachelor's in Supply Chain, Engineering or Life Sciences, with 8–10 years in biopharma supply chain.
• Experience in cell/gene therapy, biologics, or complex cold-chain modalities.
• Proven track record building or scaling supply chains in outsourced environments.

Responsibilities

• Design the operating model for global supply chain of advanced therapies.
• Lead demand and supply planning, distribution, and cold-chain logistics.
• Ensure GDP, DSCSA and related regulatory compliance and launch readiness.
• Drive cross-functional collaboration with TechOps, Quality, Regulatory and Finance.
• Oversee network design, inventory management and risk mitigation.

Skills

Demand planning

Global logistics

Cross-functional collaboration

Strategic leadership

Risk mitigation

Education

Bachelor's in Supply Chain, Engineering, or Life Sciences

Tools

SAP

Anaplan

Job description

Role

Director of Commercial Supply Chain at uniQure, responsible for building, scaling, and managing global supply chain operations for AAV gene therapies ahead of Phase 3 and commercialization. Core responsibilities include designing the operating model, demand and supply planning, distribution, cold-chain logistics, launch readiness, and ensuring compliance with GDP, DSCSA, and other regulations. The role entails leading cross‑functional collaboration with TechOps, Quality, Regulatory, Finance, and external partners, overseeing network design, inventory management, and risk mitigation to support high‑value, temperature‑sensitive therapies. Requirements: Bachelor's in Supply Chain, Engineering, or Life Sciences; 8-10 years in biopharma supply chain, with direct experience in cell/gene therapy, biologics, or complex cold-chain modalities. Proven track record in building or scaling supply chains in outsourced environments, with expertise in demand planning, distribution models, and global logistics. Preferred skills include ERP systems proficiency (SAP, Anaplan), strong financial acumen, and stakeholder management. The position demands a hands‑on leader comfortable with strategic planning and tactical execution, adept at navigating ambiguity in a fast‑growing, high‑stakes environment. The role is located in the US, with an estimated salary range of $205,000—$265,000 USD.