Director, Distribution & Trade

uniQure; United States; On-site; USD 205,000 - 265,000; Full time

Job summary

uniQure is seeking a seasoned Trade & Distribution leader in the US to implement strategy across our commercial pipeline. You will work cross-functionally with Supply Chain, Finance, Legal and Market Access to ensure smooth product flow from finished goods to end user, and manage all channel intermediaries.

The role demands 5+ years in pharma trade and distribution, experience with 3PLs and ex-US strategies, strong negotiation and communication, and travel up to 30%.

Qualifications

• Bachelor's degree required; advanced degree preferred (MBA, RPh, PharmD, MPH, MHA).
• 5+ years in pharmaceutical trade and distribution, with rare disease/gene therapy exposure.
• Experience managing 3PLs, SDs, and SPs relationships.
• Experience designing ex-US distribution strategies and knowledge of compassionate use programs.
• Strong negotiation and contract development skills in complex distribution channels.
• Launch experience in trade & distribution, preferably in rare disease/gene therapy.
• Independent contributor with strong communication and leadership when needed.
• Willingness to travel ~30%.

Responsibilities

• Develop and refine US/global channel strategies for distribution.
• Negotiate and manage relationships with channel intermediaries (3PL, SD, SP).
• Design ex-US distribution models aligned with local healthcare and reimbursement.
• Collaborate with IT to ensure data from intermediaries for ERP reporting.
• Ensure cold-chain integrity and DSCSA serialization compliance.
• Monitor channel KPIs and recommend course corrections.
• Identify new opportunities to improve efficiency and reduce costs.
• Manage distribution budget and GTN line items.
• Develop training materials to elevate distribution fluency across the organization.
• Attend industry conferences and symposiums.

Skills

Channel strategy development

3PL/SD/SP relationship management

Contract negotiation

Cross-functional collaboration

Communication skills

Regulatory compliance understanding

Education

Bachelor's degree

MBA or related advanced degree

Tools

ERP systems

Job description

Place in the Organization

At uniQure, we are delivering on the promise of gene therapy and delivering hope for patients facing urgent unmet medical needs. Every role in our organization carries profound purpose; whether you're in research, operations, access, or support, your contributions impact patients. We're seeking passionate professionals who thrive in high-stakes environments, uphold rigorous quality standards, and share our relentless commitment to transforming the lives of patients. Join us in making the impossible possible, where your expertise becomes a catalyst for life-changing treatments.

Place in the Organization

At uniQure, we are delivering on the promise of gene therapy and delivering hope for patients facing urgent unmet medical needs. Every role in our organization carries profound purpose; whether you're in research, operations, access, or support, your contributions impact patients. We're seeking passionate professionals who thrive in high-stakes environments, uphold rigorous quality standards, and share our relentless commitment to transforming the lives of patients. Join us in making the impossible possible, where your expertise becomes a catalyst for life-changing treatments.

We are looking for an individual to implement the trade & distribution strategy across uniQure’s commercial pipeline of products in the US and select countries around the world. This role requires a versatile, analytically driven professional who can operate cross-functionally across Supply Chain, Finance, Legal and Market Access to ensure a smooth flow of product throughout the entire supply chain (from finished goods to delivery to end user). This individual will directly manage all channel intermediaries (3PL, Sd, SP) involved in the distribution of uniQure’s pipeline of products.

Key Result Areas (major Duties, Accountabilities And Responsibilities)

• Develop, execute and continuously refine the US and global channel strategies for uniQure’s portfolio of products ensuring each strategy is tailored to the specific distribution dynamics for each therapy.
• Negotiate, execute, and manage all relationships with channel intermediaries (3PL, SD, SP).
• Design and implement fit-for-purpose ex-US distribution models adapted to local healthcare and reimbursement structures.
• Partner with uniQure’s IT department to ensure all intermediaries are providing all relevant product flow and financial flow data for reporting purposes (ERP system).
• Ensure cold-chain integrity, DSCSA serialization compliance, and supply chain business continuity across the distribution network.
• Design and monitor specific channel KPIs to ensure efficient supply chain dynamics and make recommendations to course correct as necessary.
• Identify, develop, and operationalize new business opportunities across the distribution network to improve efficiencies and save costs.
• Manage operational budget and oversee the financial planning for all distribution channel expenses and GTN line items.
• Collaborate to build internal capability and trade fluency across functions by developing educational resources and training materials that elevate distribution’s impact and understanding across the organization.
• Attend all pertinent industry conferences and symposiums.

Qualifications & Skills

• Bachelor’s degree required. Advanced degree preferred (MBA, RPh, Pharm D, MPH, MHA).
• Minimum 5+ years of progressive experience in the pharmaceutical trade & distribution. Preferred experience in rare disease / gene therapy.
• Demonstrated experience developing and managing 3PLs, SDs, and SPs relationships.
• Previous experience designing ex-US distribution strategies and familiarity with named patient, EAP, and compassionate use programs in international markets.
• Proven track record in contract negotiation and offer development withing a complex distribution channel environment.
• Previous launch experience in trade & distribution. Preferred launch experience in rare disease / gene therapy.
• Can operate independently as an individual contributor to drive results in a sometimes ambiguous and evolving environment.
• Strong written and verbal communication skills, including comfort level with senior management presentations.
• Compliance mindset: thorough knowledge of US and international pharmaceutical distribution regulations and an unwavering commitment to ethical business practices.
• Willingness to travel as needed (~30%).

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant, relevant years of experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from where they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

US Salary Range

$205,000—$265,000 USD

uniQure is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, sexual orientation, or gender identity), national origin, age, disability, genetic information, marital status, veteran or military status, or any other characteristic protected by applicable federal, state, or local laws.