Director, Clinical Pharmacology — Remote PK/PD Strategy

Travere Therapeutics; United States; On-site; USD 189,000 - 246,000; Full time

Benefits offered by this job

Premium health

Financial wellbeing programs

Life insurance

Retirement plan with company match

Generous PTO

Job summary

Travere Therapeutics is seeking a Director of Clinical Pharmacology to lead PK/PD strategy across clinical programs. You will shape recommendations for dose, regimen, study design, and evidence needs, and translate data into program decisions in collaboration with senior management and regulatory bodies.

You will oversee study design, modeling, and regulatory submissions while building partnerships with Research, Regulatory, and Project Management to advance rare disease therapies.

Qualifications

• PhD or PharmD in Clinical Pharmacology, Pharmaceutical Sciences, or related field with 6+ years in clinical pharmacology.
• Expertise in PK/PD, biopharmaceutics, and pharmacometrics across multiple projects.
• Demonstrated leadership in cross-functional drug development and regulatory interactions.

Responsibilities

• Lead clinical pharmacology strategy and integrate PK/PD into development plans.
• Provide strategic guidance on dose, regimen, study design, and evidence needs.
• Design and oversee PK/PD studies and modeling for early candidates.
• Support regulatory submissions with clinical pharmacology content and responses.
• Develop and author clinical pharmacology documents and reports.
• Collaborate with R&D to align pharmacology plans with program needs.

Skills

PK/PD

Pharmacokinetics

Pharmacometrics

MIDD

Cross-functional leadership

Regulatory strategy

Education

PhD in Clinical Pharmacology

PharmD in Pharmaceutical Sciences

Tools

NONMEM

R

Job description

Travere Therapeutics is seeking a Director of Clinical Pharmacology to lead PK/PD strategy across clinical programs. You will shape recommendations for dose, regimen, study design, and evidence needs, and translate data into program decisions in collaboration with senior management and regulatory bodies.

You will oversee study design, modeling, and regulatory submissions while building partnerships with Research, Regulatory, and Project Management to advance rare disease therapies.