Senior Director, Clinical Pharmacology — Remote

Travere Therapeutics; Columbus (OH); On-site; USD 189,000 - 246,000; Full time

Benefits offered by this job

Premium health benefits

Stock options

Retirement plans with company match

Generous paid time off

Job summary

Travere Therapeutics is seeking a Director of Clinical Pharmacology in San Diego. The role leads PK/PD strategy across programs, shapes dosing strategies, and partners with senior management and regulatory agencies to translate data into actionable program decisions.

The candidate will guide cross-functional teams, oversee studies, and contribute to regulatory filings while driving innovation in model-informed drug development for rare diseases.

Qualifications

• Requires 6+ years of clinical pharmacology experience.
• Experience leading PK/PD studies and modeling.
• Experience with model-informed drug development (MIDD) strategies.

Responsibilities

• Lead clinical pharmacology strategy and integrate PK/PD data into development plans.
• Provide strategic guidance on dose, regimen, study design, and evidence needs.
• Design and oversee PK/PD studies and modeling for early candidates.
• Support regulatory submissions including briefs, INDs, CTAs, and NDAs.
• Review protocols and reports for regulatory filings and address questions.
• Develop clinical pharmacology documents such as protocols and CSRs.
• Foster partnerships with R&D functions to align pharmacology plans with program needs.

Skills

PK/PD

Pharmacometrics

Leadership

Regulatory strategy

Dose selection

Cross-functional collaboration

Education

PhD or PharmD in Clinical Pharmacology

Job description

Travere Therapeutics is seeking a Director of Clinical Pharmacology in San Diego. The role leads PK/PD strategy across programs, shapes dosing strategies, and partners with senior management and regulatory agencies to translate data into actionable program decisions.

The candidate will guide cross-functional teams, oversee studies, and contribute to regulatory filings while driving innovation in model-informed drug development for rare diseases.