Crystallization Research Scientist

JMD Technologies Inc.; Boston (MA); On-site; USD 69,000 - 83,000; Full time

Job summary

JMD Technologies Inc. in Boston, MA, seeks a Crystallization Research Scientist for a 12+ month contract.

You will support laboratory-scale drug substance development, focusing on fit-for-purpose API crystallization and particle-forming processes that enable commercially viable manufacturing. Responsibilities include developing and demonstrating small-molecule API crystallization at bench scale, optimizing isolation and drying, supporting particle engineering, and collaborating with

Qualifications

• BS or MS in life sciences, chemical engineering or chemistry preferred, 2–5 years pharma industry.
• Experience in API process development and scale-up, especially crystallization.
• Fundamentals in kinetics, thermodynamics and transport phenomena.
• Familiarity with instrumentation (HPLC, GC, FTIR, Raman, XRPD, DSC, TGA).
• DOE/QbD experience and process/physical-property modeling tools; strong communication.

Responsibilities

• Develop and demonstrate small-molecule API crystallization at lab/bench scale.
• Develop and optimize API isolation and drying operations.
• Support particle engineering activities including size reduction.
• Collaborate with organic, physical, analytical chemistry teams, projects and manufacturing.

Skills

API process development

Crystallization & particle engineering

DOE / QbD concepts

Kinetics & thermodynamics

Communication & collaboration

Education

BS or MS in life sciences (Chem Eng or Chemistry preferred)

Tools

Aspen

Dynochem

MATLAB

HPLC

GC

FTIR

Raman

FBRM

DSC

TGA

XRPD

Job description

Title: Crystallization Research Scientist

Employment Type: Contract — 12+ months

Status: Accepting Candidates

About the Role

Support laboratory-scale drug substance process development, with a focus on developing fit-for-purpose API crystallization and particle-forming processes that support commercially viable manufacturing.

Key Responsibilities

• Develop and demonstrate small-molecule API crystallization processes at laboratory/bench scale.
• Develop and optimize API isolation and drying operations.
• Support particle engineering activities, including size reduction and related particle-forming operations.
• Collaborate with interdisciplinary teams spanning organic, physical, and analytical chemistry, project teams, and manufacturing.

Qualifications

• BS or MS in a life science discipline, preferably Chemical Engineering or Chemistry, with 2–5 years of pharmaceutical industry experience.
• Experience in API process development and scale-up, particularly small-molecule crystallization and particle engineering.
• Working knowledge of chemistry and chemical engineering fundamentals, including kinetics, thermodynamics, and transport phenomena.
• Familiarity with laboratory instrumentation such as HPLC, GC, FTIR, Raman, FBRM, DSC, TGA, and XRPD, as well as laboratory automation tools.
• Experience with statistical design of experiments and QbD concepts, plus familiarity with process/physical-property modeling tools such as Aspen, Dynochem, or MATLAB; strong communication and collaboration skills.

Compensation

• $50–$60/hr.
• Final compensation within the posted range will depend on qualifications, experience, and interview results.