Cryo-EM Research Scientist: Ion Channels

University of Washington Medical Center; Seattle (WA); On-site; USD 69,000 - 74,000; Full time

Job summary

The University of Washington seeks a Research Scientist/Engineer 2 in the Department of Pharmacology, Wisedchaisri Lab, to advance structural studies of voltage-gated sodium channels using cryo-EM and biochemical methods.

The role focuses on overexpression, purification, and structural characterization with insect and human channels, training others, and presenting findings at meetings.

Qualifications

• Bachelor’s degree in biology, biochemistry, molecular biology, or related field.
• Two years of laboratory experience.
• Equivalent education or experience may substitute for minimum qualifications.

Responsibilities

• Perform molecular biology techniques including PCR, cloning, sequencing, and construct generation.
• Handle mammalian and insect cell culture, expression, purification, and biochemistry.
• Carry out cryo-EM experiments: grid prep, data collection, analysis, structure determination.
• Train laboratory personnel and mentor junior members in techniques.

Skills

Molecular biology techniques

Recombinant protein expression

Cryo-EM

Cell culture

Data analysis

Education

Bachelor’s degree in biology or related field

Tools

FPLC purification

Job description

The University of Washington seeks a Research Scientist/Engineer 2 in the Department of Pharmacology, Wisedchaisri Lab, to advance structural studies of voltage-gated sodium channels using cryo-EM and biochemical methods.

The role focuses on overexpression, purification, and structural characterization with insect and human channels, training others, and presenting findings at meetings.