Computational Immunology Scientist, Multiomics

BioSpace; Cambridge (MA); Presencial; USD 150.000 - 190.000; Jornada completa

Descripción de la vacante

AbbVie Immunology in Cambridge, MA is expanding its discovery Systems Immunology team. We seek a Computational Immunology Scientist to develop computational approaches across scRNA-seq, scATAC-seq, TCR/BCR, and proteomics data to identify therapeutic targets in autoimmune diseases.

The role emphasizes cross-functional collaboration and rigorous analyses. You will work on multiomics integration, contribute to publications, and support translational insights for AbbVie pipelines.

Formación

• BS or MS in computational biology, bioinformatics, genomics or related quantitative field with relevant experience.
• Hands-on scRNA-seq, scATAC-seq or TCR/BCR analysis experience preferred.
• Proficiency in Python and/or R and Linux-based computing.
• Experience with common bioinformatics workflows and tools listed above.
• Strong statistical and multi-omics interpretation skills.

Responsabilidades

• Analyze scRNA-seq and CITE-seq with QC, integration, clustering, and annotation.
• Integrate cohorts with reference atlases and perform differential analyses.
• Analyze scATAC-seq to identify regulatory programs and peak-to-gene links.
• Analyze TCR/BCR repertoires and link to single-cell profiles.
• Integrate bulk RNA-seq and proteomics data to aid target prioritization.
• Collaborate and communicate findings, contribute to publications and presentations.

Conocimientos

Python

R

scRNA-seq analysis

scATAC-seq analysis

TCR/BCR analysis

multi-omics integration

Linux environments

Educación

BS in computational biology or related field

MS in computational biology or related field

Herramientas

Scanpy

AnnData

Cell Ranger

scvi-tools

DESeq2

GSEA

WGCNA

Descripción del empleo

AbbVie Immunology in Cambridge, MA is expanding its discovery Systems Immunology team. We seek a Computational Immunology Scientist to develop computational approaches across scRNA-seq, scATAC-seq, TCR/BCR, and proteomics data to identify therapeutic targets in autoimmune diseases.

The role emphasizes cross-functional collaboration and rigorous analyses. You will work on multiomics integration, contribute to publications, and support translational insights for AbbVie pipelines.