Computational Chemist – Drug Discovery & Modeling

Schrödinger; Boston (MA); On-site; USD 100,000 - 180,000; Full time

Benefits offered by this job

Health benefits

401k matching

Pre-tax commuter benefits

Flexible work schedule

Paid vacation time

Job summary

Schrödinger is seeking a Computational Chemist to join our Therapeutics Group in Boston. You will contribute to a wide range of drug discovery projects, applying molecular modeling, MD, and quantum methods to optimize leads and drive innovative solutions.

You will collaborate with biologists, chemists, and software engineers to troubleshoot challenges and advance Schrödinger’s discovery technologies, with an emphasis on cross-disciplinary communication and applied modeling.

Qualifications

• Ph.D. in computational chemistry, or related field.
• Robust scientific training in molecular modeling, statistical mechanics, and/or quantum mechanics; plus exposure to related areas such as lead optimization, MD, free-energy methods, ML, virtual screening, cheminformatics, ADMET modeling.

Responsibilities

• Provide computational chemistry/modeling support to active drug discovery projects while assisting and developing appropriate modeling approaches to help drive drug discovery projects and methods development.
• Troubleshoot computational problems
• Share knowledge with the greater Schrödinger Therapeutic Group (STG)
• Work closely with the internal software development teams to improve Schrödinger’s drug discovery technologies

Skills

Coding/scripting languages

Interdisciplinary collaboration

Education

Ph.D. in computational chemistry

Tools

Cheminformatics databases

Job description

Schrödinger is seeking a Computational Chemist to join our Therapeutics Group in Boston. You will contribute to a wide range of drug discovery projects, applying molecular modeling, MD, and quantum methods to optimize leads and drive innovative solutions.

You will collaborate with biologists, chemists, and software engineers to troubleshoot challenges and advance Schrödinger’s discovery technologies, with an emphasis on cross-disciplinary communication and applied modeling.