Clinical Laboratory Scientist – NGS & Molecular Tech

Prelude Corporation; Laguna Hills (CA); On-site; USD 94,000 - 104,000; Full time

Job summary

PreludeDx is seeking a licensed Clinical Laboratory Scientist to join our R&D team in Laguna Hills, CA. The ideal candidate has experience in Next Generation Sequencing (NGS) and molecular biology techniques.

Responsibilities include calibrating and maintaining equipment, running NGS workflows, data analysis, and training other staff, with CAP/CLIA compliance and thorough record-keeping. Hours are 8am to 5pm, compensation $45–$50/hour.

Qualifications

• Minimum 4 years as a certified or licensed clinical laboratory scientist.
• California Clinical Laboratory Scientist (Highly Preferred: CGMBS license).
• Experience with Macrodissection, RNA extraction and downstream analysis.
• Strong experience in development of targeted library, conducting sequencing library preparation, sequencing, and data analysis.
• Experience in project management and organization.
• Excellent record-keeping and documentation skills.
• Strong communication skills and ability to work in a team-oriented environment.
• Preferred Bachelor’s or Master’s degree in Molecular Biology, Biochemistry, or related field.
• Minimum of 4 years of molecular and histology experience within an anatomic pathology laboratory or clinical laboratory.

Responsibilities

• Ensure that the equipment is calibrated, maintained, and operated according to the manufacturer’s guidelines and standard operating procedures.
• Adheres to the CAP, CLIA and NYS regulations.
• Run protocols for sample collection, processing, storage, and tracking in LIMs to ensure the integrity and traceability of the samples throughout the NGS workflow.
• Run clinical and R&D samples for NGS and molecular biology techniques, including microdissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, data analysis, and quality control measures with appropriate NGS controls.
• Perform and train other CLS’s on established NGS and molecular biology procedures, including macrodissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, and data analysis, including quality control measures.
• Perform validation testing to ensure with selected reagents and controls to ensure the assay meets the required performance specifications.
• Perform validation studies to assess the performance characteristics of the NGS assay, including sensitivity, specificity, accuracy, precision, and reproducibility.
• Analyze and interpret data using appropriate statistical methods and software, including sensitivity, specificity, accuracy, precision and reproducibility.
• Maintain accurate records and documentation of experiments and results.

Job description

PreludeDx is seeking a licensed Clinical Laboratory Scientist to join our R&D team in Laguna Hills, CA. The ideal candidate has experience in Next Generation Sequencing (NGS) and molecular biology techniques.

Responsibilities include calibrating and maintaining equipment, running NGS workflows, data analysis, and training other staff, with CAP/CLIA compliance and thorough record-keeping. Hours are 8am to 5pm, compensation $45–$50/hour.