Clinical Laboratory Scientist

PreludeDx; Laguna Hills (CA); On-site; USD 70,000 - 90,000; Full time

Job summary

A leading biotechnology company in California is seeking a licensed CLS to perform NGS and molecular biology techniques. Candidates should have a minimum of 4 years' experience and appropriate certifications. Responsibilities include sample processing, validation testing, and data analysis. The ideal candidate is detail-oriented with strong communication skills and project management experience. This is a full-time position at a mid-senior level.

Qualifications

• Minimum 4 years as a certified or licensed clinical laboratory scientist.
• California Clinical Laboratory Scientist license preferred.
• Experience with NextGen sequencing instruments.

Responsibilities

• Calibrate and maintain equipment as per guidelines.
• Run NGS protocols and ensure sample integrity.
• Perform validation testing and analyze data.

Skills

Strong communication skills

Data analysis

Well-organized

Project management

Experience with macrodissection

Education

Bachelor's or Master's degree in Molecular Biology, Biochemistry, or related field

Job description

Overview

We are seeking a highly motivated and skilled licensed CLS to join our team. The ideal candidate will have experience in running Next Generation Sequencing (NGS) and knowledge of molecular biology techniques.

Essential Responsibilities

• Ensure that the equipment is calibrated, maintained, and operated according to the manufacturer\'s guidelines and standard operating procedures.
• Adhere to the CAP, CLIA and NYS regulations.
• Run protocols for sample collection, processing, storage, and tracking in LIMs to ensure the integrity and traceability of the samples throughout the NGS workflow.
• Run clinical and R&D samples for NGS and molecular biology techniques, including microdissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, data analysis, and quality control measures with appropriate NGS controls.
• Perform and train other CLSs on established NGS and molecular biology procedures, including macrodissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, and data analysis, including quality control measures.
• Perform validation testing to ensure the assay meets the required performance specifications with selected reagents and controls.
• Perform validation studies to assess the performance characteristics of the NGS assay, including sensitivity, specificity, accuracy, precision, and reproducibility.
• Analyze and interpret data using appropriate statistical methods and software, including sensitivity, specificity, accuracy, precision and reproducibility.
• Maintain accurate records and documentation of experiments and results.

Qualifications

• Minimum 4 years as a certified or licensed clinical laboratory scientist.
• California Clinical Laboratory Scientist (Highly Preferred: California Clinical Genetic Molecular Biologist Scientist license - CGMBS).
• Well-organized, open-minded, decisive, and flexible. Strong communication, writing skills, and extensive computer experience are necessary.
• Experience with macrodissection, RNA extraction and downstream analysis.
• Strong experience in development of targeted libraries, conducting sequencing library preparation, sequencing, and data analysis.
• Experience in project management and organization.
• Excellent record-keeping and documentation skills; ability to work in a team-oriented environment.
• Validation and SOP writing experience a plus.
• Must have superior work ethic, be driven and results-oriented; comfortable in a fast-paced environment.
• Excellent oral and written communication skills.
• Preferred Bachelor\'s or Master\'s degree in Molecular Biology, Biochemistry, or related field.
• Anatomic or Clinical Pathology experience.
• Prior experience with NextGen sequencing instruments.
• Minimum of 4 years of molecular and histology experience within an anatomic pathology laboratory or clinical laboratory.

Seniority level

• Mid-Senior level

Employment type

• Full-time

Job function

• Research, Analyst, and Information Technology

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