Cell Therapy Analytical Development Associate II

NantHealth Inc.

Northern (KY)

Hybrid

USD 83,000 - 92,000

Full time

4 days ago
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Benefits offered by this job

Discretionary bonus
Equity award

Job summary

ImmunityBio is seeking a Research Associate II, Analytical Development in Torrey Pines, CA to support adoptive cell therapy projects. You will develop, optimize and validate bioassays and help operate the lab with cross-functional teams.

The role requires a Bachelor's with 3+ years or a Master’s with 1+ years in a biology-related field, experience in immunoassays (Mass Cytometry CytOf, flow cytometry, HPLC, MSD, ELISA, Q-PCR) and cell therapy knowledge; a fast-paced environment awaits with

Qualifications

  • Bachelor’s degree with 3+ years of experience in Biology, Biochemistry, Immunology or a related field.
  • Master’s degree with 1+ years in Biology, Biochemistry, Immunology or a related field.
  • Experience with immunoassay technologies such as, Mass Cytometry (CytOf), flow cytometry, HPLC, ELISA and MSD and molecular assays (Q-PCR) to support cell characterization as required.
  • Experience with cell therapy products including NK and T cells is a plus.
  • Competent in handling and maintaining mammalian cell culture in a BSL2 Laboratory.

Responsibilities

  • Perform cell-based assays with minimal supervision to support analytical and process development team.
  • Maintain cells as required for various assays.
  • Perform cell characterization using Mass Cytometry (CytOf), Flow Cytometry, HPLC, and MSD Platform.
  • Maintain, calibrate and operate cell analytical equipment and instruments.
  • Develop standard operating procedures, analytical test methods, analytical sampling plans and batch records.
  • Provide support to cross-functional teams to advance development of cell therapy products.
  • Design and execute analytical method development and qualification in support of lead candidate selection, process development, product release and stability, and product characterization.
  • Design and execute experiments to develop, qualify, and transfer cell-based potency methods for the testing and release of pipeline products.
  • Provide support to the bioanalytical testing of samples for immunogenicity and biomarkers.
  • Performs ad-hoc and cross-functional duties and/or projects as assigned to support business needs and provide developmental opportunities.

Skills

Mass Cytometry CytOf
Flow Cytometry
HPLC
MSD Platform
FlowJo
Prism
JMP
PLA 3.0
Immunoassay data analysis
Mammalian cell culture
Q-PCR

Education

Bachelor’s degree in Biology, Biochemistry, Immunology or related field
Master’s degree in Biology, Biochemistry, Immunology or related field

Tools

CytOf
FlowJo
Prism
JMP
Q-PCR

Job description

ImmunityBio is seeking a Research Associate II, Analytical Development in Torrey Pines, CA to support adoptive cell therapy projects. You will develop, optimize and validate bioassays and help operate the lab with cross-functional teams.

The role requires a Bachelor's with 3+ years or a Master’s with 1+ years in a biology-related field, experience in immunoassays (Mass Cytometry CytOf, flow cytometry, HPLC, MSD, ELISA, Q-PCR) and cell therapy knowledge; a fast-paced environment awaits with

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