Cardiac Organoid Scientist II

Frederick National Laboratory for Cancer Research; Frederick (MD); On-site; USD 106,000 - 151,000; Full time

Job summary

Frederick National Laboratory for Cancer Research seeks a Scientist II to lead the development of human iPSC-derived cardiac organoid platforms within the SOM Cardiac Laboratory. You will apply stem cell biology, cardiac development concepts, and advanced phenotyping to create robust organoid models that capture structural, cellular, and functional heart features.

You'll drive methodology development, validation, and standardization, coordinating cross-disciplinary projects and contributing to

Qualifications

• PhD in a related biomedical field (Biomedical Engineering, Stem Cell Biology, Cardiac Biology, or closely related).
• Minimum of two years postdoctoral experience.
• Ability to obtain and maintain a security clearance.
• Proficiency with Microsoft Office tools.

Responsibilities

• Design, develop, optimize, and validate methods to generate human iPSC-derived cardiac organoids with reproducibility and scalability.
• Lead projects on cardiac organoid development, maturation, and functional characterization.
• Establish SOPs, QC metrics, and acceptance criteria for iPSC culture and organoid production.
• Develop quantitative assays to assess organoid morphology, viability, lineage identity, and function.
• Collaborate with multidisciplinary teams to integrate datasets for comprehensive organoid profiling.
• Mentor junior researchers and drive scientific reporting and publication activity.

Skills

Microsoft Office

Security clearance

Independent researcher

Scientific communication

Education

PhD degree

Tools

Immunofluorescence

Confocal microscopy

Flow cytometry

qPCR

Transcriptomics

Single-cell RNA sequencing

High-content imaging

Job description

Frederick National Laboratory for Cancer Research seeks a Scientist II to lead the development of human iPSC-derived cardiac organoid platforms within the SOM Cardiac Laboratory. You will apply stem cell biology, cardiac development concepts, and advanced phenotyping to create robust organoid models that capture structural, cellular, and functional heart features.

You'll drive methodology development, validation, and standardization, coordinating cross-disciplinary projects and contributing to