Biomarker Method Lead Scientist

KCAS Bio; Kansas City (MO); Sur place; USD 120 000 - 180 000; Plein temps

Avantages offerts par ce poste

Stock ownership program

KCAS University access

Wellness & community programs

Résumé du poste

KCAS Bio in Kansas City is seeking a Sr. Scientist to advance biomarker method development. You will design, develop, optimize, and troubleshoot ligand binding assays (LBA) to support biomarker work in bioanalytical settings.

You will partner with internal teams and clients, providing scientific guidance and training, ensuring robust assay performance and regulatory compliance across studies.

Qualifications

• Bachelor’s, Master’s, or PhD in Biology, Biochemistry, Immunology, or related field with at least 5 years in a bioanalytical laboratory environment.
• Demonstrated depth of biomarker method development, including biomarker assay development, optimization, and troubleshooting.
• Hands-on experience with LBA platforms (ELISA, MSD) or similar immunoassays.
• Ability to independently design experiments, evaluate assay performance, troubleshoot challenges, and optimize conditions.
• Strong understanding of assay performance characteristics (precision, accuracy, sensitivity, selectivity, specificity, robustness).
• Experience in regulated bioanalytical environments (QA, GLP/GxP).
• Excellent written and verbal communication with ability to mentor staff.

Responsabilités

• Lead the design, development, optimization, and troubleshooting of ligand binding assays with a focus on biomarker methods.
• Design experiments and independently evaluate assay performance to establish robust methods.
• Develop and optimize assay conditions, reagents, controls, and workflows for complex challenges.
• Apply scientific judgment to evaluate performance characteristics and troubleshoot issues.
• Support method qualification, validation, and transfer activities as appropriate.
• Provide technical training and mentorship to junior staff.
• Communicate findings, recommendations, and risks to internal teams and clients.
• Collaborate with QA and scientific teams to ensure compliant activities.

Connaissances

Biomarker methods

LBA platforms

Experimental design

Data interpretation

Root-cause analysis

Mentorship

Regulatory awareness

Communication

Formation

Bio/Immuno PhD

Outils

ELISA

MSD

Bioanalytical instruments

Description du poste

KCAS Bio in Kansas City is seeking a Sr. Scientist to advance biomarker method development. You will design, develop, optimize, and troubleshoot ligand binding assays (LBA) to support biomarker work in bioanalytical settings.

You will partner with internal teams and clients, providing scientific guidance and training, ensuring robust assay performance and regulatory compliance across studies.