Biologics Purification Scientist – Large Molecule

Ampcus Inc; Spring House (PA); On-site; USD 80,000 - 86,000; Full time

Job summary

Ampcus Inc. is seeking a Chemistry Scientist 2 for large-molecule/drug substance purification in Spring House, PA, onsite. Role focuses on process development, purification strategies, and hands-on experimentation to support biologics processes.

Responsibilities include interpreting analytical data, training colleagues, and contributing to DOE efforts with emphasis on scalable models and PAT approaches. Strong documentation and collaboration in a cross-functional team are essential.

Qualifications

• Bachelor’s, Master’s, or Ph.D. in Chemistry or related discipline with industry experience.
• Hands-on LC systems experience (Protein A, CEX, AEX).
• Experience with biologics purification and SP-TFF / UF/DF.
• Strong documentation and notebook skills.

Responsibilities

• Design and perform process development experiments for biologics purification.
• Execute studies on LC, SP-TFF, UF/DF and filtration operations.
• Apply reduced-scale models and support PAT approaches.
• Prepare solutions, sample handling, data submission, and documentation.
• Interpret analytical data to inform purification strategies and decisions.
• Contribute to DOE and protein/large-molecule purification innovation.
• Write memos and present data internally.
• Train and mentor others on techniques and equipment.

Skills

Protein A chromatography

SP-TFF / UF/DF

Data interpretation

Lab documentation

Education

Bachelor’s degree in Chemistry or related

Master’s degree in Chemistry/biotech

Tools

KTA Pure

KTA Avant

Job description

Ampcus Inc. is seeking a Chemistry Scientist 2 for large-molecule/drug substance purification in Spring House, PA, onsite. Role focuses on process development, purification strategies, and hands-on experimentation to support biologics processes.

Responsibilities include interpreting analytical data, training colleagues, and contributing to DOE efforts with emphasis on scalable models and PAT approaches. Strong documentation and collaboration in a cross-functional team are essential.