Senior Biologics Purification Scientist I/II

ABBVIE

North Chicago (IL)

On-site

USD 110,000 - 209,000

Full time

14 days+

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Job summary

AbbVie is seeking a Senior Scientist in Biologics Purification to lead small-scale antibody purification and develop robust bioprocess strategies. You will design chromatography workflows, perform analytical characterizations, and apply DOE with automation to improve separations.

Collaboration across teams and clear results presentation are essential to drive innovation in downstream processes. The role emphasizes translational biology, supports in vitro/in vivo studies, and contributes to

Qualifications

BS/MS/PhD in a relevant field with typically 0–3 years (PhD), 5–7 years (MS), or 8–10 years (BS) of experience
Deep proficiency in bioprocessing, column chromatography, and antibody-based biotherapeutics manufacturing is required
Expertise with AKTA chromatography systems is required
Experience operating high throughput automated liquid handling systems for chromatography applications (i.e. Tecan, Hamilton) is desirable
Design of Experiments (DOE) studies with high throughput automation for protein production scale-up is preferable
Familiarity with programming languages (Python) and developing Bioinformatics/AI tools is a plus
Strong understanding of molecular and post-translational attributes of biologics
Exceptional analytical, communication, and presentation skills
Collaborative spirit and dedication to scientific excellence

Responsibilities

Lead small-scale (<1L) purification of multi-specific antibody biologics to support critical research assays and studies
Design and execute advanced chromatography techniques and robust bioprocess development strategies to address production impurities and liabilities to deliver high quality antibody biologics
Execute rigorous analytical characterization of molecules, end products, by-products, and process intermediates
Apply Design of Experiments (DOE) with high throughput automation to optimize chromatography conditions for enhanced separation and resolution of complex protein mixtures
Drive innovation to support continuous improvement in downstream biologics processes and advance automation initiatives
Collaborate with multidisciplinary teams, translating molecular insights into functional results
Present findings clearly to diverse audiences and document results with rigor