Bioinformatics Scientist – Genome Editing Center

NC State University

Raleigh (NC)

On-site

USD 90,000 - 130,000

Full time

18 hours ago
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Benefits offered by this job

Childcare benefits
Wellness programs
Wellness & Recreation Membership

Job summary

NC State University in Raleigh, NC seeks a Bioinformatics Scientist to lead genome editing efforts across crop species, directing target identification, guide RNA design, and off-target analyses. The role includes developing sequencing strategies, transforming into high-throughput workflows, and mentoring Ph.D.

researchers and postdocs in a collaborative setting. The successful candidate will contribute to publications, patents, and grant proposals, while collaborating with cross-department

Qualifications

  • Ph.D. and 5+ years research experience in molecular biology and genome engineering.
  • Advanced knowledge of molecular biology, genome engineering, and plant genome editing techniques.
  • Ability to lead complex research activities and mentor personnel.

Responsibilities

  • Lead genome editing research across crop species, including target identification and guide RNA design.
  • Develop genome editing protocols, molecular assays, and sequencing strategies.
  • Sequence plant genomes and analyze editing outcomes to support projects and publications.
  • Provide scientific leadership and mentorship to researchers and trainees.
  • Develop SOPs and training materials to ensure research quality and continuity.

Skills

Molecular biology
Genome engineering
Plant genome editing
Sequencing data analysis
Research leadership
Cross-functional collaboration

Education

Ph.D. in a relevant field

Tools

TaqMan
PCR
Nanopore
Illumina

Job description

Bioinformatics Scientist – Genome Editing Center
About the Department

As part of the Land Grant University, the Department of Entomology and Plant Pathology in the College of Agriculture and Life Sciences at North Carolina State University is composed of over 40 faculty that direct a diverse portfolio of programs in teaching, research, and extension. Collectively, these strengths not only serve our clientele and our science but also provide a rich environment for graduate education and training that can be tailored to the specific career interests of the student, irrespective of whether they prefer training in the basic sciences or are preparing for a career in extension. Our education and research programs provide graduate and undergraduate students with unique hands‑on learning opportunities using the latest technologies. Entomology and Plant Pathology houses the Plant Disease and Insect Clinic, the Larry Grand Mycological Herbarium, Micropropagation and Repository Unit, Structural Pest Management Training Facility, an Insect Museum with 1.9 million vouchered insects, and the Center for Integrated Fungal Research.

The College of Agriculture and Life Sciences houses 12 Academic departments with 294 faculty, 2,891 undergraduate students and 899 graduate students. The College is home to 18 research stations strategically located across the state that enhances our interactions with our farmers, stakeholders, and industry partners. Our strategic plan, Growing Our Future 2023-2030 is accessible here https://units.cals.ncsu.edu/cals-strategic-plan/.

Wolfpack Perks and Benefits

As a Pack member, you belong here, and can enjoy exclusive perks designed to enhance your personal and professional well‑being. As you consider this opportunity, we encourage you to review our Employee Value Proposition and learn more about what makes NC State the best place to learn and work for everyone.

Attain Work‑life balance with our Childcare benefits, Wellness & Recreation Membership, and Wellness Programs that aim to build a thriving wolfpack community.

Disclaimer: Perks and Benefit eligibility is based on Part-Time or Full-Time Employment status. Eligibility and Employer Sponsored Plans can be found within each of the links offered.

Key Responsibilities
  • Lead genome editing research across crop species, including genomic target identification, guide RNA design, off‑target analysis, and evaluation of editing outcomes.
  • Develop and refine genome editing protocols, molecular assays, sequencing strategies, and high‑throughput genotyping platforms using technologies such as TaqMan, PCR, Nanopore, and Illumina. Develop approaches for transformation, tissue culture, vector construction, and molecular characterization.
  • Sequence ornamental plant genomes, identify lead candidates for genome editing, design guide RNAs, and analyze genome editing outcomes in support of the Overdevest Sponsored Project Agreement with Overdevest Nurseries, which accounts for approximately 60% of the position.
  • Analyze genomic, molecular, and statistical data to inform research conclusions and support publications, patents, grant proposals, and sponsored research activities.
  • Provide scientific and technical leadership, consultation, training, and mentorship to Ph.D. scientists, postdoctoral scholars, visiting scientists, and other research personnel.
  • Develop standardized protocols, standard operating procedures (SOPs), and training materials to support research quality, consistency, and continuity. Collaborate across departments and with research partners to advance genome editing projects and research capabilities.
Other Responsibilities

In addition to the core responsibilities of this role, there may be occasional opportunities to take on additional duties. This offers an opportunity to build on your skills, explore new areas, and gain a deeper understanding of the department’s operations.

Qualifications
Minimum Education and Experience

Ph.D. and 5+ years research experience in molecular biology and specifically vector construction, assay development, molecular analysis, and genome engineering in industry and academic settings, including leadership of teams.

Other Required Qualifications
  • Advanced knowledge of molecular biology, genome engineering, and plant genome editing techniques.
  • Knowledge of molecular assay development, sequencing technologies, and genomic data analysis.
  • Ability to develop and optimize research protocols and novel techniques.
  • Ability to independently lead complex research activities, interpret genomic and molecular data, and draw research conclusions.
  • Skills in scientific leadership, cross‑functional collaboration, and training and mentoring research personnel.
Preferred Qualifications
  • 5+ years of industry experience including leading teams of scientists
  • 10+ years research experience in molecular biology and specifically vector construction, assay development, molecular analysis, and genome engineering in industry and academic settings, including leadership of teams.
Required License(s) or Certification(s)

N/A

Valid NC Driver's License required

Valid NC Driver's License required No

Commercial Driver's License required

Commercial Driver's License required No

EEO

NC State University is an equal opportunity employer. All qualified applicants will receive equal opportunities for employment without regard to age, color, disability, gender identity, genetic information, national origin, race, religion, sex (including pregnancy), sexual orientation, and veteran status. The University encourages all qualified applicants, including protected veterans and individuals with disabilities, to apply. Individuals with disabilities requiring disability‑related accommodations in the application and interview process are welcome to contact 919-513-0574 to speak with a representative of the Office of Equal Opportunity. Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. Degree(s) must be obtained prior to start date in order to meet qualifications and receive credit. NC State University participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States.

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