Bioinformatics Director: Epigenomics & AI for Precision Medicine

Dinamo Biotechnologies; San Francisco (CA); On-site; USD 180,000 - 320,000; Full time

Job summary

Dinamo Biotechnologies is seeking a Director of Bioinformatics to own the computational strategy end to end, from raw methylation sequencing data to validated, regulatory-grade responder signatures. You will build and lead a team spanning pipeline engineering, algorithms, and AI, while staying hands-on on the hardest problems and collaborating across biology, regulatory, and business functions.

You will partner with molecular biology, clinical, regulatory/CDx and business development teams and

Qualifications

• PhD in bioinformatics, computational biology, statistics, CS or related field required.
• 8+ years in computational biology/bioinformatics with 3+ years leading teams in industry.
• Hands-on experience with DNA methylation data (WGBS/EM-seq/TAPS) and epigenomics.

Responsibilities

• Define and execute computational roadmap for methylation-based responder stratification across autoimmune indications.
• Develop methods and tools (statistical, ML, AI) for high-dimensional omics data.
• Drive production-grade, reproducible pipelines from data processing to model deployment.
• Build scalable cloud/HPC infrastructure and data management for CLIA-ready development.

Skills

Python

Cloud/HPC

Nextflow

Snakemake

WDL

Docker

CI/CD

Git

Education

PhD in bioinformatics

Tools

AWS

Nextflow

Snakemake

Docker

WDL

Job description

Dinamo Biotechnologies is seeking a Director of Bioinformatics to own the computational strategy end to end, from raw methylation sequencing data to validated, regulatory-grade responder signatures. You will build and lead a team spanning pipeline engineering, algorithms, and AI, while staying hands-on on the hardest problems and collaborating across biology, regulatory, and business functions.

You will partner with molecular biology, clinical, regulatory/CDx and business development teams and