Bioinformatics Analyst

Lifespan; Providence (RI); On-site; USD 68,000 - 112,000; Full time

Job summary

Brown University Health seeks a Bioinformatics Analyst to analyze clinical Next Generation Sequencing data, help develop data analysis pipelines, and organize and maintain databases within the Pathology department.

Under supervision, you will participate in daily workflows, contribute to validation of new NGS tests, and support database/webtool development with strong genomics knowledge and programming skills.

Qualifications

• Bachelor's degree required; master's preferred.
• Strong genomics knowledge with programming skills (Python/Perl/Java).
• Experience with DNA-seq/RNA-seq tools (BWA, GATK, STAR, Samtools).
• Knowledge of SQL/HTML/CSS/Apache for database/webtools.

Responsibilities

• Participates in daily clinical bioinformatics workflow, analyzes data for test validation.
• Assists in developing analysis pipelines and evaluating new methods.
• Assists in developing databases and webtools.

Skills

Programming/Scripting (Python, Perl, 1

NGS data analysis

SQL/HTML/CSS/Apache

Bioinformatics tools knowledge

CAP/CLIA familiarity

Education

Bachelor's Degree

Master's Degree in Bioinformatics or related field

Tools

BWA

GATK

STAR

Samtools

Perl

Python

Java

SQL

Job description

SUMMARY

Under the general supervision of the Bioinformatics Scientist, Department Manager, Laboratory Directors, and Pathologists, and in accordance with established policies and procedures, the Bioinformatics Analyst performs independently in the Department of Pathology. The Bioinformatics Analyst will be responsible for analyzing clinical Next Generation Sequencing data, contributing to the development of data analysis pipelines, and organizing and maintaining databases.

Brown University Health employees are expected to successfully role model the organization's values of Compassion, Accountability, Respect, and Excellence as these values guide our everyday actions with patients, customers and one another.

RESPONSIBILITIES

• Participates in the daily clinical bioinformatics workflow, such as DNA-seq and RNA-seq data analysis. Analyzes the clinical data for the validation of new Next Generation Sequencing tests. Assists with preparation of validation summaries of the new Next Generation Sequencing tests.
• Assists in developing analysis pipelines for Next Generation Sequencing tests. Evaluates analytical aspects of emerging analysis methods.
• Assists in the development of databases and webtools.

MINIMUM QUALIFICATIONS

• Bachelor's Degree required.
• Master's Degree in Bioinformatics, Computational Biology, Computer Science or a related field is preferred.
• Demonstrates strong scientific understanding of genomics.
• Demonstrates proficiency in programming and scripting skills (e.g, Perl, Python, or Java).
• Demonstrates knowledge of DNA-seq and RNA-seq data analysis tools (e.g., BWA, GATK, STAR, Samtools).
• Demonstrates knowledge of database and webtool development (e.g., SQL, HTML, CSS, Apache).
• Maintains up-to-date knowledge of bioinformatics data analysis tools
• Familiarity with CAP/CLIA lab setting is preferred but not required.

EXPERIENCE

• At least two years of industry or clinical lab experience. Experience in developing computational approaches for cancer genome and/or germline analysis is highly desirable.
• Excellent teamwork, time management, and organizational skills.

WORK ENVIRONMENT AND PHYSICAL REQUIREMENTS

• This position requires the Bioinformatics Analyst to work closely with Bioinformatics Scientists, Medical Technologists, Management, Laboratory Directors and Pathologists.
• Ability to operate equipment and instruments and to perform all procedures within assigned laboratory section and interpret them for accuracy. Physical and visual dexterity necessary to conduct and interpret analysis. Visual strain is encountered while closely examining data.

INDEPENDENT ACTION

• Ability to work independently in a fast-paced, multidisciplinary environment.
• Ability to multi-task and work on multiple clinical and developmental projects simultaneously.
• Analyst functions independently within the department's policies and procedures. Refers specific complex issues to the Bioinformatics Scientist, Manager, Laboratory Directors, or Pathologists when clarification of policies and procedures is required.

SUPERVISORY RESPONSIBILITY

• None.

Pay Range

$67,724.80-$111,716.80

Brown University Health is committed to providing equal employment opportunities and maintaining a work environment free from all forms of unlawful discrimination and harassment.

Location

Rhode Island Hospital - 593 Eddy Street Providence, Rhode Island 02903

Work Type

M-F 8:30am-5:00pm

Work Shift

Day

Daily Hours

8 hours

Driving Required

No