Bioassay Development & Screening Scientist – VelocImmune

Regeneron

Village of Tarrytown (NY)

On-site

USD 85,000 - 115,000

Full time

14 days+

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Job summary

Regeneron is seeking an Associate Scientist to join the Bioassay Development and Screening group within the Therapeutic Proteins Department, supporting the VelocImmune antibody pipeline. You will develop and perform cell-based assays to reveal how antibodies act on molecular function and signaling, contributing to discovery and characterization of therapeutic molecules.

The role is onsite in Tarrytown, NY, with collaboration across neuroscience, immunology, and other teams.

Qualifications

Bachelor's in biology or related field with at least 3 years of experience, or a Master's with 0–3 years.
Proficiency in planning, executing, and analyzing experiments and presenting data to colleagues.
Experience with mammalian cell culture and hands-on technical proficiency with in vitro and cell-based assays.
Familiarity with in vitro assays interrogating molecular and cellular function and signal transduction pathways.
Must thrive in a fast-paced, collaborative, and multi-tasking environment, and bring strong organizational skills to daily work.
Preferred qualifications include: cell engineering experience, multi-well assay experience, cell-based functional assay experience, flow cytometry and imaging experience, immunology experience, antibody development experience and primary immune cell assay experience.

Responsibilities

Develop and perform cell-based assays in support of VelocImmune antibody pipeline.
Contribute to in vitro characterization and screening across neuroscience, immunology, and other disease areas.
Develop cell lines and characterize them using transfection, transduction, and CRISPR.
Apply flow cytometry and imaging to characterize cell-based systems.
Develop and optimize bioassays, including luciferase reporter and internalization assays.
Perform primary cell-based assays, including those involving immune cells.
Run high-throughput functional screens using 96- and 384-well plate formats.
Analyze data, organize results, and communicate findings clearly to your supervisor.
Document experiments in an electronic notebook and present data effectively at team meetings.