Associate Scientist, Bioassay Development and Screening

Regeneron; Village of Tarrytown (NY); On-site; USD 85,000 - 115,000; Full time

Job summary

Regeneron is seeking an Associate Scientist to join the Bioassay Development and Screening group within the Therapeutic Proteins Department, supporting the VelocImmune antibody pipeline. You will develop and perform cell-based assays to reveal how antibodies act on molecular function and signaling, contributing to discovery and characterization of therapeutic molecules.

The role is onsite in Tarrytown, NY, with collaboration across neuroscience, immunology, and other teams.

Qualifications

• Bachelor's in biology or related field with at least 3 years of experience, or a Master's with 0–3 years.
• Proficiency in planning, executing, and analyzing experiments and presenting data to colleagues.
• Experience with mammalian cell culture and hands-on technical proficiency with in vitro and cell-based assays.
• Familiarity with in vitro assays interrogating molecular and cellular function and signal transduction pathways.
• Must thrive in a fast-paced, collaborative, and multi-tasking environment, and bring strong organizational skills to daily work.
• Preferred qualifications include: cell engineering experience, multi-well assay experience, cell-based functional assay experience, flow cytometry and imaging experience, immunology experience, antibody development experience and primary immune cell assay experience.

Responsibilities

• Develop and perform cell-based assays in support of VelocImmune antibody pipeline.
• Contribute to in vitro characterization and screening across neuroscience, immunology, and other disease areas.
• Develop cell lines and characterize them using transfection, transduction, and CRISPR.
• Apply flow cytometry and imaging to characterize cell-based systems.
• Develop and optimize bioassays, including luciferase reporter and internalization assays.
• Perform primary cell-based assays, including those involving immune cells.
• Run high-throughput functional screens using 96- and 384-well plate formats.
• Analyze data, organize results, and communicate findings clearly to your supervisor.
• Document experiments in an electronic notebook and present data effectively at team meetings.

Skills

cell culture

flow cytometry

imaging

data analysis

experimental planning

communication

Education

Bachelor's in Biology or related field

Master's degree in Biology or related field

Tools

CRISPR

transfection

transduction

luciferase assay

FlowJo

GraphPad Prism

Job description

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Associate Scientist to join our Bioassay Development and Screening group within the Therapeutic Proteins Department, supporting our VelocImmune antibody pipeline. In this role, you will develop and perform cell-based assays that reveal how antibodies act on molecular function and signaling, playing an integral role in the discovery and characterization of therapeutic molecules across diverse disease areas, while collaborating with scientists across neuroscience, immunology, and other therapeutic teams.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

• Location: Tarrytown, NY
• Work model: Onsite

Discover your role:

• Develop and perform cell-based assays in support of the company's VelocImmune antibody pipeline
• Contribute to the in vitro characterization and screening of therapeutic antibodies across neuroscience, immunology, and other disease areas
• Develop cell lines and characterize them using cell engineering techniques such as transfection, transduction, and CRISPR
• Apply flow cytometry and imaging to characterize cell-based systems
• Develop and optimize bioassays, including luciferase reporter and internalization assays
• Perform primary cell-based assays, including those involving immune cells
• Run high-throughput functional screens using 96- and 384-well plate formats
• Analyze data, organize results, and communicate findings clearly to your supervisor
• Document experiments in an electronic notebook and present data effectively at team meetings

This role requires:

• Bachelor's in biology or a related field with at least 3 years of relevant professional experience, or a Master's degree with 0-3 years of relevant experience
• Proficiency in planning, executing, and analyzing experiments in addition to communicating clearly and presenting data to colleagues
• Experience with mammalian cell culture and hands-on technical proficiency with in vitro and cell-based assays
• Familiarity with in vitro assays interrogating molecular and cellular function and signal transduction pathways
• Must thrive in a fast-paced, collaborative, and multi-tasking environment, and bring strong organizational skills to daily work
• Preferred qualifications include: cell engineering experience, multi-well assay experience, cell-based functional assay experience, flow cytometry and imaging experience, immunology experience, antibody development experience and primary immune cell assay experience

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

Does this sound like you? We are committed to building a workplace with an inclusive culture.