Automated iPSC Cell Culture Scientist

GAP Solutions, Inc.; Bethesda (MD); Sur place; USD 110 000 - 140 000; Plein temps

Résumé du poste

GAP Solutions, Inc. supports NIH's National Institute on Aging in Bethesda, MD, conducting automated cell culture research to investigate ADRD genetic pathways using human iPSC models.

The role involves planning experiments, developing differentiation protocols for neural lineages, and operating high-throughput robotic systems. Strong data analysis, GLP, and programming skills are required.

Qualifications

• Master's degree in cell biology, molecular biology, genetics, biochemistry, bioengineering, chemical engineering, or related field.
• Minimum of 2 years of related experience.
• Good Laboratory Practices (GLP).
• Skilled in R and Seurat.
• Experience in programming (VENUS, Visual Basic, C++, MATLAB, or Python).
• Proficiency with automated liquid handling robots.
• Hands-on experience with cell culture, especially iPSCs.
• Experience with operating and programming liquid handling platforms (Hamilton, TECAN, Beckman, Agilent).
• Knowledge of laboratory disposal methods and procedures.
• Experience with MS Office Suite.

Responsabilités

• Plan and administer biological research programs.
• Work with staff to characterize genetic pathways for ADRD using human cell-based models.
• Perform large-scale iPSC cell culture experiments on liquid handling platforms.
• Design and implement new automated methods for cell culture and analysis.
• Coordinate and supervise technicians and scientists on workflows.
• Develop differentiation protocols for iPSC lines into neurons, astrocytes, and microglia.
• Conduct image analysis to assess mutation effects on phenotypes.
• Maintain detailed digital and physical lab records and notebooks.
• Present results in team and department meetings.
• Train staff on instrumentation and software.

Connaissances

R

Seurat

Python

MATLAB

C++

Visual Basic

VENUS

Python programming

iPSC culture

liquid handling robots

Formation

Master's degree in cell biology or related field

Outils

Hamilton liquid handling platform

TECAN liquid handling platform

Beckman robotics

Agilent instruments

Description du poste

GAP Solutions, Inc. supports NIH's National Institute on Aging in Bethesda, MD, conducting automated cell culture research to investigate ADRD genetic pathways using human iPSC models.

The role involves planning experiments, developing differentiation protocols for neural lineages, and operating high-throughput robotic systems. Strong data analysis, GLP, and programming skills are required.