Associate Scientist II: Ligand Optimization & NGS/AI Design

Soufflé Therapeutics; Watertown (MA); Sur place; USD 80 000 - 110 000; Plein temps

Résumé du poste

Soufflé Therapeutics, a biotech company in Watertown, MA, seeks an Associate Scientist II to advance ligand optimization and data-driven workflows in our pre-clinical programs. You will run hands-on experiments and help build AI/ML guided design strategies to engineer cell-type specific therapeutics.

The role emphasizes NGS, deep sequencing, and collaboration with data science to expand our ligand engineering platform, with direct impact on our pre-clinical pipeline and cross-functional teams in

Qualifications

• 1–2 years of relevant experience with an MS, or 2–3 years with a BS.
• Experience with next-generation sequencing (NGS), flow cytometry, and cell culture.

Responsabilités

• Support ligand optimization efforts to meet pre-clinical program needs.
• Perform NGS workflows to bolster ligand library screening.
• Collaborate with data science to design and generate ligand libraries using AI/ML models.
• Conduct ligand library screening using yeast or phage display methods.
• Support production and screening teams to produce reagents and evaluate ligands for discovery activities.

Connaissances

NGS

Flow cytometry

Cell culture

Formation

BS or MS in a relevant scientific discipline

Outils

Yeast display

Phage display

Computational protein design tools

Antibody engineering

Description du poste

Soufflé Therapeutics, a biotech company in Watertown, MA, seeks an Associate Scientist II to advance ligand optimization and data-driven workflows in our pre-clinical programs. You will run hands-on experiments and help build AI/ML guided design strategies to engineer cell-type specific therapeutics.

The role emphasizes NGS, deep sequencing, and collaboration with data science to expand our ligand engineering platform, with direct impact on our pre-clinical pipeline and cross-functional teams in