Associate Scientist II

Integrated Resources, Inc.; Cambridge (MA); On-site; USD 60,000 - 90,000; Full time

Job summary

Integrated Resources, Inc. seeks a hands-on chemist to join the DS Process Development Group.

You will support oligonucleotide product synthesis method development, optimization and scale-up, and perform in-process analytical testing. You will collaborate with research and process scientists to develop robust processes for Client chemistries, ensure quality, safety, and compliance, and help maintain a clean laboratory and accurate records.

Qualifications

• Basic understanding of analytical techniques (pH, osmolality, conductivity, HPLC, LC-MS). Hands-on experience preferred.
• Experience with record-keeping and laboratory documentation practices is required.
• Good communication and teamwork in a fast-paced environment with aggressive timelines.

Responsibilities

• Support oligonucleotide product synthesis method development, optimization and scale-up.
• Execute in-process analytical testing.
• Collaborate with researchers to develop robust processes for Client chemistries.

Skills

Analytical techniques

Oligonucleotide synthesis

Lab documentation

Team communication

Education

BS in Chemistry or Chemical Engineering

Job description

The successful candidate will be a part of the Client’s - DS Process Development Group, responsible for the process development to incorporate Client chemistries into our manufacturing platform.

Summary of Key Responsibilities:

• Support oligonucleotide - Product synthesis method development, optimization and scale-up
• Execution of in-process analytical testing
• Working with research and process scientists to develop robust processes for Client chemistries

Skills:

• Basic understanding of analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC-MS etc.). Related hands-on experience is preferred. Knowledge of oligonucleo - Product manufacture process including phosphoramidite chemistry, chromatography, ultrafiltration etc. is a plus.
• Experience in record-keeping and excellent laboratory documentation practice are required. Strong commitment to high laboratory and scientific standard; ability to maintain a safe, clean, and orderly laboratory work environment; assist in routine lab and equipment maintenance.
• Good communication skills are a must for this position. The successful candidate must be a responsible and proactive individual who is able to work as a team player in a highly dynamic environment with aggressive timelines.

Education:

BS in Chemistry or Chemical Engineering with 1-3 years of lab experience, preferably in an industrial setting