Associate Director, Translational PK/PD

Scorpion Therapeutics; Pennsylvania; On-site; USD 180,000 - 260,000; Full time

Benefits offered by this job

annual bonus

long-term incentive

Job summary

Scorpion Therapeutics seeks a Translational PK/PD Scientific Associate Director to lead model-based decisions in drug discovery. You will act as an expert PK/PD modeler in cross-functional teams, integrating data to inform dose selection and target prioritization.

You will design experiments and modeling plans for forward/reverse translation, guide automated workflows, mentor junior colleagues, and communicate across departments to advance translational strategies.

Qualifications

• Education as stated: advanced degree in PK/PD or related field (or equivalent experience).
• Hands-on translational PKPD modeling using MATLAB, OSP Suite, Monolix, and R.
• Expertise in experimental design, data analysis, statistics, and interpretation.

Responsibilities

• Serve as expert PK/PD modeler in cross-functional teams to inform drug discovery decisions.
• Integrate in vitro and in vivo data to build PKPD, PBPK, QSP platforms for translation.
• Collaborate to design experimental studies and modeling plans for candidate optimization and translational strategy.
• Guide design of automated workflows implementing modeling platforms to inform human PK/PD and dose projections.
• Provide scientific/modeling guidance to junior colleagues.
• Demonstrate strong leadership and cross-department communication.

Skills

PK/PD modeling

Translational modeling

R&D collaboration

Mathematical problem solving

Education

Master's degree in PK/PD or related field

PharmD

PhD in related field

Tools

MATLAB

OSP Suite

Monolix

R

Job description

The Translational PK/PD Scientific Associate Director will:

• Serve as expert PK/PD modeler in cross-functional teams, providing model-informed decisions about drug discovery, modality selection, and dose prediction.
• Integrate in vitro and in vivo data to build PKPD, PBPK, QSP, or other mechanistic modeling platforms to support forward/reverse translation for established and novel targets.
• Collaborate to design experimental studies and modeling plans to identify/optimize candidates and guide translational strategy.
• Guide design of automated workflows implementing modeling platforms to inform human PK/PD and dose projections.
• Provide scientific/modeling guidance to junior colleagues.
• Demonstrate strong leadership and communication across departments.

Qualifications:

• Education: Master's (8+ years), PharmD (6+ years), or Ph.D. (4+ years) in pharmacokinetics/pharmacodynamics, mathematics, applied mathematics, systems/computational biology, chemical/biomedical engineering, statistics/biostatistics, or related field; experience with increasing responsibility in drug discovery/development.

Required experience/skills:

• Hands-on translational PKPD modeling using tools such as Matlab, OSP Suite, Monolix, R for biologics/protein therapeutics/peptides.
• Expert experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics.

Preferred experience/skills:

• Interdisciplinary team experience and collaborative problem scoping/planning.
• Novel translational modeling strategies or automated workflows using PBPK, QSP, or related mechanistic modeling.

Benefits:

• annual bonus and long-term incentive (if applicable).