Associate Director, Translational Medicine & Genetics

Alnylam Pharmaceuticals, Inc.; Cambridge, Northern (MA, KY); Hybrid; USD 180,000 - 280,000; Full time

Job summary

Alnylam Pharmaceuticals, Inc. in Cambridge, MA seeks an Associate Director of Translational Genetics and Medicine to integrate medicine with human genetics data, guide early translational strategies, and collaborate across Research, Early Development and Clinical teams to advance targets into Phase 2 trials.

The role emphasizes leadership in biomarker discovery, cross-functional collaboration, and rapid translation of discoveries into clinical programs within a dynamic, team-driven environment.

Qualifications

• MD or MD/PhD with subspecialty and broad disease exposure.
• Experience translating basic science to clinical context.
• Strong manuscript drafting and leadership in cross-functional teams.
• Familiarity with clinical trial landscapes and trial design input.

Responsibilities

• Integrate knowledge of medicine with human data to generate and vet novel hypotheses.
• Lead early translational and clinical relationships with external experts to support biomarker sourcing and modeling.
• Evaluate scientific rationale and feasibility of indications for new targets guiding preclinical strategies.
• Lead early biomarker strategy across programs with in-house data scientists and biologists.
• Represent Translational Research from lead target identification to Phase 2 trials, engaging stakeholders and contributing to trial design.

Skills

Scientific communication

Translational relevance

Cross-disciplinary collaboration

Biomedical data interpretation

Education

MD or MD/PhD

Job description

Alnylam Pharmaceuticals, Inc. in Cambridge, MA seeks an Associate Director of Translational Genetics and Medicine to integrate medicine with human genetics data, guide early translational strategies, and collaborate across Research, Early Development and Clinical teams to advance targets into Phase 2 trials.

The role emphasizes leadership in biomarker discovery, cross-functional collaboration, and rapid translation of discoveries into clinical programs within a dynamic, team-driven environment.