Associate Director, Translational Medicine Clinical Lead-Immunology

Johnson & Johnson; North Carolina; Hybrid; USD 155,000 - 267,000; Full time

Job summary

A leading company in healthcare innovation seeks an Associate Director, Translational Medicine Clinical Lead to drive the development of transformational medicines for immunological disorders. This role involves leading clinical trials and collaborating with cross-functional teams to accelerate the Immunology pipeline. Candidates should possess an MD or MD/PhD and have a strong background in clinical research and immunology. Join us in pioneering the path from lab to life while championing patients every step of the way.

Benefits

Medical Insurance

Dental Insurance

Vision Insurance

401(k) Plan

Vacation

Sick Leave

Holiday Pay

Qualifications

• Minimum of 3 years of industry and/or translational research experience required.
• Strong track record in publications is preferred.
• Willingness and ability to travel, including trans-Atlantic travel (up to ~10%) is required.

Responsibilities

• Design and execution of early clinical trials through PoC including experimental medicine studies.
• Lead a cross-functional trial team to deliver on study milestones and commitments.
• Prepare and/or direct the preparation and review of protocols and clinical study reports.

Skills

Immunology

Leadership

Clinical Research

Education

MD or MD/PhD

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Clinical Development & Research – MD

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America, US337 MA Cambridge - 301 Binney St

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

About Immunology

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

We are searching for the best talent for an Associate Director, Translational Medicine Clinical Lead, Translational Science & Medicine to be in Spring House, PA, La Jolla, CA or Cambridge, MA.

As Immunology Leaders, we know immunology is vital to human health. Driven by a relentless focus on patient unmet needs, we will redefine treatments for immune diseases by delivering transformational and accessible therapies and regimens to patients with immune-mediated disease. For more than two decades we have been a world leader in the development of transformational medicines, establishing one of the strongest, first-in-class portfolios and pipelines in the industry, including the first tumor necrosis factor (TNF) inhibitor, and first interleukin (IL)-12 and IL-23 inhibitors. We tirelessly push the boundaries of science and creativity, applying our deep disease insights, novel pathway science, new technologies, and treatment modalities to restore immune homeostasis.

The Associate Director, Translational Medicine (TM), will be a program and experimental medicine leader in the Immunology Translational Science and Medicine (TSM) function. In this position, the Associate Director, TM, will decisively contribute to accelerating the Immunology pipeline from portfolio entry to Proof-of-Concept (PoC).

The Associate Director, TM, will function as a clinical lead/study responsible physician on early development programs and trials. They will contribute to creating translational plans for programs that are aligned with the overall TA strategy and with relevant disease area and/or pathway strategies. They will be empowered to lead a cross-functional clinical trial team to deliver on the trial’s major execution milestones within governance-approved timeline and budget commitments. This responsibility extends end to end for clinical trials: from initial protocol design to continued monitoring and problem solving on trial execution to the analysis, interpretation, and communication of study results. This role will partner with translational science and deep engagement with investigators and external experts is expected. In this leadership role they will be supported by the senior leaders within the Translational Science and Medicine function, including the relevant disease area leaders (both in clinical development and biomarker science) and a clinical study responsible scientist. The span of studies in scope are phase 1 (including focused experimental medicine studies) through Proof of Concept.

This position reports into a Senior Director of the Translational Medicine (TM) group. Within TM, the Associate Director will be part of the Translational Medicine Program Lead group which has primary responsibility within TSM for creating and implementing innovative translational plans for the portfolio assets. TSM is a group within the Immunology Therapeutic Area, consisting of Translational Medicine and Translational Science (TS) has expertise in the clinical study of immunologic disease, immunologic pathways, and in early clinical trial design and execution. TS has expertise in biomarker development, disease biology research, and in the application of immunology and data science technologies to support drug development. Organizationally, TSM serves as a pivotal bridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases. This position will play a ‘dual role’, contributing both scientific and clinical development expertise to TSM projects.

Responsibilities:

1. Design and execution of program translational strategies integrating both disease and pathway approaches.
2. Design and execution of early clinical trials through PoC including experimental medicine studies.
3. Lead a cross-functional trial team to deliver on study milestones and commitments.
   • Collaborate with translational science on the development and implementation of clinical biomarker and patient segmentation strategies.
4. Support experimental medicine studies.
   • Support Business Development, including due diligence activities.
   • Represent TM on early development teams.
   • Represent TM for project teams when presenting to portfolio, project, and governance meetings.
   • Lead or participate in cross-functional working groups such as scientific and safety review boards.
   • Identify and collaborate with academic translational sites to optimize the translational strategy and plans for programs.
   • Prepare and/or direct the preparation and review of protocols, clinical study reports and translational medicine sections of Translational plans, IBs, INDs, abstracts, manuscripts, and technical reports.
   • Responsible for presentation of results and updates of projects at department, project, corporate and scientific meetings.

Qualifications:

1. MD or MD/PhD degree required.
2. Minimum of 3 years of industry and/or translational research experience required.
3. Training in Immunology strongly preferred.
4. Subspecialty medical training in Dermatology, Rheumatology or Respiratory is preferred but not required.
5. Demonstrated supervisory and/or leadership experience with clinical and/or research teams is required.
6. Strong track record in publications is preferred.
7. Willingness and ability to travel, including trans-Atlantic travel (up to ~10%) is required.
8. Location is in the United States.

The anticipated base pay range for this position is: $155,000 - $$266,800

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis.

Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

• Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
• This position is eligible to participate in the Company’s long-term incentive program.
• Employees are eligible for the following time off benefits:
• Vacation – up to 120 hours per calendar year
• Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar year
• Holiday pay, including Floating Holidays – up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year
• Additional information can be found through the link below. https://www.careers.jnj.com/employee-benefits

The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center ([e-mail]) or contact AskGS to be directed to your accommodation resource.

#LI-Hybrid

#LI-Onsite

Additional Description for Pay Transparency: